ACSS1 (acyl-CoA synthetase short chain family member 1)

2017-08-01  

Identity

HGNC
LOCATION
20p11.21
LOCUSID
ALIAS
ACAS2L,ACECS1,AceCS2L
FUSION GENES

Other Information

Locus ID:

NCBI: 84532
MIM: 614355
HGNC: 16091
Ensembl: ENSG00000154930

Variants:

dbSNP: 84532
ClinVar: 84532
TCGA: ENSG00000154930
COSMIC: ACSS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154930ENST00000323482Q9NUB1
ENSG00000154930ENST00000376726Q5TF43
ENSG00000154930ENST00000432802Q9NUB1
ENSG00000154930ENST00000537502Q9NUB1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Glycolysis / GluconeogenesisKEGGko00010
Pyruvate metabolismKEGGko00620
Propanoate metabolismKEGGko00640
Glycolysis / GluconeogenesisKEGGhsa00010
Pyruvate metabolismKEGGhsa00620
Propanoate metabolismKEGGhsa00640
Metabolic pathwaysKEGGhsa01100
Carbon metabolismKEGGhsa01200
Carbon metabolismKEGGko01200
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase 1 - Functionalization of compoundsREACTOMER-HSA-211945
Ethanol oxidationREACTOMER-HSA-71384

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380422182024Identifying Acss1, Mtfp1 and Oxct1 as key regulators and promising biomarkers of sarcopenia in various models.1
380422182024Identifying Acss1, Mtfp1 and Oxct1 as key regulators and promising biomarkers of sarcopenia in various models.1
273630212016Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma.12
275398512016Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth.33
273630212016Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma.12
275398512016Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth.33
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.7
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.17
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.7
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.17
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
197248952009Association of gene polymorphisms with chronic kidney disease in Japanese individuals.0

Citation

Dessen P

ACSS1 (acyl-CoA synthetase short chain family member 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56946/deep-insight-explorer/js/gene-fusions-explorer/