UQCR10 (ubiquinol-cytochrome c reductase, complex III subunit X)

2017-08-01 Affiliation

Identity

HGNC

UQCR10

LOCATION

22q12.2

LOCUSID

29796

ALIAS

HSPC051,HSPC119,HSPC151,QCR9,UCCR7.2,UCRC

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 29796
MIM: 610843
HGNC: 30863
Ensembl: ENSG00000184076

Variants:

dbSNP: 29796
ClinVar: 29796
TCGA: ENSG00000184076
COSMIC: UQCR10

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000184076	ENST00000330029	Q9UDW1
ENSG00000184076	ENST00000401406	Q9UDW1

Expression (GTEx)

100

150

200

250

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Oxidative phosphorylation	KEGG	ko00190
Alzheimer's disease	KEGG	ko05010
Huntington's disease	KEGG	ko05016
Oxidative phosphorylation	KEGG	hsa00190
Alzheimer's disease	KEGG	hsa05010
Parkinson's disease	KEGG	hsa05012
Huntington's disease	KEGG	hsa05016
Cardiac muscle contraction	KEGG	hsa04260
Cardiac muscle contraction	KEGG	ko04260
Metabolic pathways	KEGG	hsa01100
Cytochrome bc1 complex	KEGG	hsa_M00152
Cytochrome bc1 complex	KEGG	M00152
Non-alcoholic fatty liver disease (NAFLD)	KEGG	hsa04932
Non-alcoholic fatty liver disease (NAFLD)	KEGG	ko04932
Metabolism	REACTOME	R-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transport	REACTOME	R-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	REACTOME	R-HSA-163200
Respiratory electron transport	REACTOME	R-HSA-611105

References

Pubmed ID	Year	Title	Citations
27401149	2016	Novel fusion genes and chimeric transcripts in ependymal tumors.	7
27401149	2016	Novel fusion genes and chimeric transcripts in ependymal tumors.	7
22277967	2012	Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing.	201
22277967	2012	Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing.	201
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20
16054089	2005	Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing.	622
16054089	2005	Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing.	622

Citation

Dessen P

UQCR10 (ubiquinol-cytochrome c reductase, complex III subunit X)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56988/js/favicon/manifest.json