TRIM47 (tripartite motif containing 47)

2017-10-01 Affiliation

Identity

HGNC

TRIM47

LOCATION

17q25.1

LOCUSID

91107

ALIAS

GOA,RNF100

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 91107
MIM: 611041
HGNC: 19020
Ensembl: ENSG00000132481

Variants:

dbSNP: 91107
ClinVar: 91107
TCGA: ENSG00000132481
COSMIC: TRIM47

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000132481	ENST00000254816	Q96LD4
ENSG00000132481	ENST00000585333	K7EQ30
ENSG00000132481	ENST00000586495	K7EJ63
ENSG00000132481	ENST00000587339	A0A0M3HER3

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
38614226	2024	TRIM47-CDO1 axis dictates hepatocellular carcinoma progression by modulating ferroptotic cell death through the ubiquitin‒proteasome system.	0
38614226	2024	TRIM47-CDO1 axis dictates hepatocellular carcinoma progression by modulating ferroptotic cell death through the ubiquitin‒proteasome system.	0
36203070	2022	TRIM47 promotes glioma angiogenesis by suppressing Smad4.	0
36288633	2022	TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.	1
36203070	2022	TRIM47 promotes glioma angiogenesis by suppressing Smad4.	0
36288633	2022	TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.	1
33350849	2021	Trim47 overexpression correlates with poor prognosis in gastric cancer.	8
33529753	2021	TRIM47 accelerates aerobic glycolysis and tumor progression through regulating ubiquitination of FBP1 in pancreatic cancer.	16
33833824	2021	Upregulated Tripartite Motif 47 Could Facilitate Glioma Cell Proliferation and Metastasis as a Tumorigenesis Promoter.	4
34433666	2021	TRIM47 activates NF-κB signaling via PKC-ε/PKD3 stabilization and contributes to endocrine therapy resistance in breast cancer.	17
33350849	2021	Trim47 overexpression correlates with poor prognosis in gastric cancer.	8
33529753	2021	TRIM47 accelerates aerobic glycolysis and tumor progression through regulating ubiquitination of FBP1 in pancreatic cancer.	16
33833824	2021	Upregulated Tripartite Motif 47 Could Facilitate Glioma Cell Proliferation and Metastasis as a Tumorigenesis Promoter.	4
34433666	2021	TRIM47 activates NF-κB signaling via PKC-ε/PKD3 stabilization and contributes to endocrine therapy resistance in breast cancer.	17
32603762	2020	Knockdown of TRIM47 inhibits glioma cell proliferation, migration and invasion through the inactivation of Wnt/β-catenin pathway.	10

Citation

Dessen P

TRIM47 (tripartite motif containing 47)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57159/js/lib/favicon/gene-fusions-explorer/