ATP5F1E (ATP synthase F1 subunit epsilon)

2018-02-01 Affiliation

Identity

HGNC

ATP5F1E

LOCATION

20q13.32

LOCUSID

514

ALIAS

ATP5E,ATPE,MC5DN3

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 514
MIM: 606153
HGNC: 838
Ensembl: ENSG00000124172

Variants:

dbSNP: 514
ClinVar: 514
TCGA: ENSG00000124172
COSMIC: ATP5F1E

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000124172	ENST00000243997	P56381
ENSG00000124172	ENST00000395659	P56381
ENSG00000124172	ENST00000395663	P56381

Pathways

Pathway	Source	External ID
Oxidative phosphorylation	KEGG	ko00190
Alzheimer's disease	KEGG	ko05010
Huntington's disease	KEGG	ko05016
Oxidative phosphorylation	KEGG	hsa00190
Alzheimer's disease	KEGG	hsa05010
Parkinson's disease	KEGG	hsa05012
Huntington's disease	KEGG	hsa05016
Metabolic pathways	KEGG	hsa01100
F-type ATPase, eukaryotes	KEGG	hsa_M00158
F-type ATPase, eukaryotes	KEGG	M00158
Metabolism	REACTOME	R-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transport	REACTOME	R-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	REACTOME	R-HSA-163200
Formation of ATP by chemiosmotic coupling	REACTOME	R-HSA-163210

References

Pubmed ID	Year	Title	Citations
36625260	2023	Hsa_circ_0079480 enhances cell proliferation, migration, and invasion in colorectal cancer through miR-498/ATP5E axis.	0
36625260	2023	Hsa_circ_0079480 enhances cell proliferation, migration, and invasion in colorectal cancer through miR-498/ATP5E axis.	0
26079849	2015	Molecular Analysis by Gene Expression of Mitochondrial ATPase Subunits in Papillary Thyroid Cancer: Is ATP5E Transcript a Possible Early Tumor Marker?	6
26079849	2015	Molecular Analysis by Gene Expression of Mitochondrial ATPase Subunits in Papillary Thyroid Cancer: Is ATP5E Transcript a Possible Early Tumor Marker?	6
24067918	2013	Cell surface F1/FO ATP synthase contributes to interstitial flow-mediated development of the acidic microenvironment in tumor tissues.	12
24067918	2013	Cell surface F1/FO ATP synthase contributes to interstitial flow-mediated development of the acidic microenvironment in tumor tissues.	12
20026007	2010	Knockdown of F1 epsilon subunit decreases mitochondrial content of ATP synthase and leads to accumulation of subunit c.	22
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20
20026007	2010	Knockdown of F1 epsilon subunit decreases mitochondrial content of ATP synthase and leads to accumulation of subunit c.	22
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20
19016746	2008	Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells.	7
19016746	2008	Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells.	7

Citation

Dessen P

ATP5F1E (ATP synthase F1 subunit epsilon)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57284/gene-fusions-explorer/case-report-explorer/haematological-explorer/