ATP5F1E (ATP synthase F1 subunit epsilon)

2018-02-01  

Identity

HGNC
LOCATION
20q13.32
LOCUSID
ALIAS
ATP5E,ATPE,MC5DN3

Other Information

Locus ID:

NCBI: 514
MIM: 606153
HGNC: 838
Ensembl: ENSG00000124172

Variants:

dbSNP: 514
ClinVar: 514
TCGA: ENSG00000124172
COSMIC: ATP5F1E

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124172ENST00000243997P56381
ENSG00000124172ENST00000395659P56381
ENSG00000124172ENST00000395663P56381

Pathways

PathwaySourceExternal ID
Oxidative phosphorylationKEGGko00190
Alzheimer's diseaseKEGGko05010
Huntington's diseaseKEGGko05016
Oxidative phosphorylationKEGGhsa00190
Alzheimer's diseaseKEGGhsa05010
Parkinson's diseaseKEGGhsa05012
Huntington's diseaseKEGGhsa05016
Metabolic pathwaysKEGGhsa01100
F-type ATPase, eukaryotesKEGGhsa_M00158
F-type ATPase, eukaryotesKEGGM00158
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.REACTOMER-HSA-163200
Formation of ATP by chemiosmotic couplingREACTOMER-HSA-163210

References

Pubmed IDYearTitleCitations
366252602023Hsa_circ_0079480 enhances cell proliferation, migration, and invasion in colorectal cancer through miR-498/ATP5E axis.0
366252602023Hsa_circ_0079480 enhances cell proliferation, migration, and invasion in colorectal cancer through miR-498/ATP5E axis.0
260798492015Molecular Analysis by Gene Expression of Mitochondrial ATPase Subunits in Papillary Thyroid Cancer: Is ATP5E Transcript a Possible Early Tumor Marker?6
260798492015Molecular Analysis by Gene Expression of Mitochondrial ATPase Subunits in Papillary Thyroid Cancer: Is ATP5E Transcript a Possible Early Tumor Marker?6
240679182013Cell surface F1/FO ATP synthase contributes to interstitial flow-mediated development of the acidic microenvironment in tumor tissues.12
240679182013Cell surface F1/FO ATP synthase contributes to interstitial flow-mediated development of the acidic microenvironment in tumor tissues.12
200260072010Knockdown of F1 epsilon subunit decreases mitochondrial content of ATP synthase and leads to accumulation of subunit c.22
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
200260072010Knockdown of F1 epsilon subunit decreases mitochondrial content of ATP synthase and leads to accumulation of subunit c.22
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
190167462008Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells.7
190167462008Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells.7

Citation

Dessen P

ATP5F1E (ATP synthase F1 subunit epsilon)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57284/js/case-report-explorer/haematological-explorer/