ATP5PF (ATP synthase peripheral stalk subunit F6)

2018-02-01 Affiliation

Identity

HGNC

ATP5PF

LOCATION

21q21.3

LOCUSID

522

ALIAS

ATP5,ATP5A,ATP5J,ATPM,CF6,F6

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 522
MIM: 603152
HGNC: 847
Ensembl: ENSG00000154723

Variants:

dbSNP: 522
ClinVar: 522
TCGA: ENSG00000154723
COSMIC: ATP5PF

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000154723	ENST00000284971	P18859
ENSG00000154723	ENST00000284971	Q6IB54
ENSG00000154723	ENST00000400087	P18859
ENSG00000154723	ENST00000400087	Q6IB54
ENSG00000154723	ENST00000400090	P18859
ENSG00000154723	ENST00000400090	Q6IB54
ENSG00000154723	ENST00000400093	P18859
ENSG00000154723	ENST00000400093	Q6IB54
ENSG00000154723	ENST00000400094	P18859
ENSG00000154723	ENST00000400094	Q6IB54
ENSG00000154723	ENST00000400099	A8MUH2
ENSG00000154723	ENST00000457143	P18859

Pathways

Pathway	Source	External ID
Oxidative phosphorylation	KEGG	ko00190
Alzheimer's disease	KEGG	ko05010
Huntington's disease	KEGG	ko05016
Oxidative phosphorylation	KEGG	hsa00190
Alzheimer's disease	KEGG	hsa05010
Parkinson's disease	KEGG	hsa05012
Huntington's disease	KEGG	hsa05016
Metabolic pathways	KEGG	hsa01100
F-type ATPase, eukaryotes	KEGG	hsa_M00158
F-type ATPase, eukaryotes	KEGG	M00158
Metabolism	REACTOME	R-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transport	REACTOME	R-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	REACTOME	R-HSA-163200
Formation of ATP by chemiosmotic coupling	REACTOME	R-HSA-163210

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
29484395	2018	Identification of candidate genes and long non-coding RNAs associated with the effect of ATP5J in colorectal cancer.	2
29484395	2018	Identification of candidate genes and long non-coding RNAs associated with the effect of ATP5J in colorectal cancer.	2
26659871	2016	Mitochondrial Inhibitory Factor Protein 1 Functions as an Endogenous Inhibitor for Coupling Factor 6.	1
26659871	2016	Mitochondrial Inhibitory Factor Protein 1 Functions as an Endogenous Inhibitor for Coupling Factor 6.	1
24124598	2013	Over-expression of the ATP5J gene correlates with cell migration and 5-fluorouracil sensitivity in colorectal cancer.	8
24124598	2013	Over-expression of the ATP5J gene correlates with cell migration and 5-fluorouracil sensitivity in colorectal cancer.	8
22038518	2012	Coupling factor 6-induced activation of ecto-F1F(o) complex induces insulin resistance, mild glucose intolerance and elevated blood pressure in mice.	4
22038518	2012	Coupling factor 6-induced activation of ecto-F1F(o) complex induces insulin resistance, mild glucose intolerance and elevated blood pressure in mice.	4
20953793	2011	Heterogeneous patterns of tissue injury in NARP syndrome.	14
20953793	2011	Heterogeneous patterns of tissue injury in NARP syndrome.	14
20811295	2010	Overexpression of coupling factor 6 causes cardiac dysfunction under high-salt diet in mice.	0
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20
20811295	2010	Overexpression of coupling factor 6 causes cardiac dysfunction under high-salt diet in mice.	0
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20
19106112	2009	Coupling factor 6 enhances Src-mediated responsiveness to angiotensin II in resistance arterioles and cells.	4

Citation

Dessen P

ATP5PF (ATP synthase peripheral stalk subunit F6)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57348/favicon/gene-explorer/