IFI35 (interferon induced protein 35)

2018-07-01  

Identity

HGNC
LOCATION
17q21.31
LOCUSID
ALIAS
IFP35
FUSION GENES

Other Information

Locus ID:

NCBI: 3430
MIM: 600735
HGNC: 5399
Ensembl: ENSG00000068079

Variants:

dbSNP: 3430
ClinVar: 3430
TCGA: ENSG00000068079
COSMIC: IFI35

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000068079ENST00000415816P80217
ENSG00000068079ENST00000438323P80217

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon alpha/beta signalingREACTOMER-HSA-909733

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
343628452021IFP35 family proteins promote neuroinflammation and multiple sclerosis.10
343628452021IFP35 family proteins promote neuroinflammation and multiple sclerosis.10
327810672020IFI35 as a biomolecular marker of neuroinflammation and treatment response in multiple sclerosis.6
327810672020IFI35 as a biomolecular marker of neuroinflammation and treatment response in multiple sclerosis.6
293508812018Interferon-induced protein 35 inhibits endothelial cell proliferation, migration and re-endothelialization of injured arteries by inhibiting the nuclear factor-kappa B pathway.20
293508812018Interferon-induced protein 35 inhibits endothelial cell proliferation, migration and re-endothelialization of injured arteries by inhibiting the nuclear factor-kappa B pathway.20
280645412017The role of IFI35 in lupus nephritis and related mechanisms.11
281099792017Interferon (IFN)-induced protein 35 (IFI35) negatively regulates IFN-β-phosphorylated STAT1-RIG-I-CXCL10/CCL5 axis in U373MG astrocytoma cells treated with polyinosinic-polycytidylic acid.14
290384652017NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury.32
280645412017The role of IFI35 in lupus nephritis and related mechanisms.11
281099792017Interferon (IFN)-induced protein 35 (IFI35) negatively regulates IFN-β-phosphorylated STAT1-RIG-I-CXCL10/CCL5 axis in U373MG astrocytoma cells treated with polyinosinic-polycytidylic acid.14
290384652017NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury.32
276396182016Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.8
276396182016Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.8
263424642015Trim21 regulates Nmi-IFI35 complex-mediated inhibition of innate antiviral response.22

Citation

Dessen P

IFI35 (interferon induced protein 35)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57542/css/js/lib/gene-explorer/