FAM210B (family with sequence similarity 210 member B)

2018-07-01  

Identity

HGNC
FAM210B
LOCATION
20q13.2
LOCUSID
116151
ALIAS
5A3,C20orf108,dJ1167H4.1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 116151
MIM: 618722
HGNC: 16102
Ensembl: ENSG00000124098

Variants:

dbSNP: 116151
ClinVar: 116151
TCGA: ENSG00000124098
COSMIC: FAM210B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124098ENST00000371384Q96KR6
ENSG00000124098ENST00000437418H0Y456

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
384367712024Mendelian randomization study on causal association of FAM210B with drug-induced lupus.1
384367712024Mendelian randomization study on causal association of FAM210B with drug-induced lupus.1
363741042022Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis.2
363741042022Elucidation of the Role of FAM210B in Mitochondrial Metabolism and Erythropoiesis.2
303669822018FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity.20
303669822018FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity.20
285943982017Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.31
285943982017Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.31
269685492016Identification of a novel putative mitochondrial protein FAM210B associated with erythroid differentiation.10
269685492016Identification of a novel putative mitochondrial protein FAM210B associated with erythroid differentiation.10
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
190645722008Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.8
190645722008Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women.8

Citation

Dessen P

FAM210B (family with sequence similarity 210 member B)

Atlas Genet Cytogenet Oncol Haematol. 2018-07-01

Online version: http://atlasgeneticsoncology.org/gene/57569/case-report-explorer/