GOLIM4 (golgi integral membrane protein 4)

2019-04-01  

Identity

HGNC
LOCATION
3q26.2
LOCUSID
ALIAS
GIMPC,GOLPH4,GPP130,P138
FUSION GENES

Other Information

Locus ID:

NCBI: 27333
MIM: 606805
HGNC: 15448
Ensembl: ENSG00000173905

Variants:

dbSNP: 27333
ClinVar: 27333
TCGA: ENSG00000173905
COSMIC: GOLIM4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173905ENST00000309027F8W785
ENSG00000173905ENST00000470487O00461

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Intra-Golgi trafficREACTOMER-HSA-6811438

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
360541642022CircRNA RNF10 inhibits tumorigenicity by targeting miR-942-5p/GOLIM4 axis in breast cancer.1
360541642022CircRNA RNF10 inhibits tumorigenicity by targeting miR-942-5p/GOLIM4 axis in breast cancer.1
337221962021MiR-105-3p acts as an oncogene to promote the proliferation and metastasis of breast cancer cells by targeting GOLIM4.9
341801332021RBFOX2/GOLIM4 Splicing Axis Activates Vesicular Transport Pathway to Promote Nasopharyngeal Carcinogenesis.12
337221962021MiR-105-3p acts as an oncogene to promote the proliferation and metastasis of breast cancer cells by targeting GOLIM4.9
341801332021RBFOX2/GOLIM4 Splicing Axis Activates Vesicular Transport Pathway to Promote Nasopharyngeal Carcinogenesis.12
300686972018Golgi integral membrane protein 4 manipulates cellular proliferation, apoptosis, and cell cycle in human head and neck cancer.9
300686972018Golgi integral membrane protein 4 manipulates cellular proliferation, apoptosis, and cell cycle in human head and neck cancer.9
287688232017Manganese-induced trafficking and turnover of GPP130 is mediated by sortilin.7
287688232017Manganese-induced trafficking and turnover of GPP130 is mediated by sortilin.7
264468392015Induced oligomerization targets Golgi proteins for degradation in lysosomes.17
264468392015Induced oligomerization targets Golgi proteins for degradation in lysosomes.17
237610682013Shiga toxin-binding site for host cell receptor GPP130 reveals unexpected divergence in toxin-trafficking mechanisms.25
237610682013Shiga toxin-binding site for host cell receptor GPP130 reveals unexpected divergence in toxin-trafficking mechanisms.25
201300812010Manganese-induced trafficking and turnover of the cis-Golgi glycoprotein GPP130.44

Citation

Dessen P

GOLIM4 (golgi integral membrane protein 4)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57968/cancer-prone-explorer/haematological-explorer/