DNTTIP1 (deoxynucleotidyltransferase terminal interacting protein 1)

2019-05-01  

Identity

HGNC
DNTTIP1
LOCATION
20q13.12
LOCUSID
116092
ALIAS
C20orf167,Tdif1,dJ447F3.4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 116092
MIM: 611388
HGNC: 16160
Ensembl: ENSG00000101457

Variants:

dbSNP: 116092
ClinVar: 116092
TCGA: ENSG00000101457
COSMIC: DNTTIP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101457ENST00000372622Q9H147
ENSG00000101457ENST00000415790F2Z2A4
ENSG00000101457ENST00000435014H7C1J2
ENSG00000101457ENST00000449078H0Y501
ENSG00000101457ENST00000456939H7C1M5

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
356898522022DNTTIP1 promotes nasopharyngeal carcinoma metastasis via recruiting HDAC1 to DUSP2 promoter and activating ERK signaling pathway.9
356898522022DNTTIP1 promotes nasopharyngeal carcinoma metastasis via recruiting HDAC1 to DUSP2 promoter and activating ERK signaling pathway.9
350086762021TdIF1-LSD1 Axis Regulates Epithelial-Mesenchymal Transition and Metastasis via Histone Demethylation of E-Cadherin Promoter in Lung Cancer.3
350086762021TdIF1-LSD1 Axis Regulates Epithelial-Mesenchymal Transition and Metastasis via Histone Demethylation of E-Cadherin Promoter in Lung Cancer.3
298555442018Critical role of deoxynucleotidyl transferase terminal interacting protein 1 in oral cancer.13
298555442018Critical role of deoxynucleotidyl transferase terminal interacting protein 1 in oral cancer.13
256197432015Definition of the transcription factor TdIF1 consensus-binding sequence through genomewide mapping of its binding sites.5
256197432015Definition of the transcription factor TdIF1 consensus-binding sequence through genomewide mapping of its binding sites.5
238743962013TdIF1 recognizes a specific DNA sequence through its Helix-Turn-Helix and AT-hook motifs to regulate gene transcription.4
238743962013TdIF1 recognizes a specific DNA sequence through its Helix-Turn-Helix and AT-hook motifs to regulate gene transcription.4
212583442011Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.281
212583442011Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.281
212583442011Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.281
212583442011Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.281
176637232007Identification of functional domains in TdIF1 and its inhibitory mechanism for TdT activity.7

Citation

Dessen P

DNTTIP1 (deoxynucleotidyltransferase terminal interacting protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2019-05-01

Online version: http://atlasgeneticsoncology.org/gene/57988/gene-explorer/favicon/hgnc