EGFLAM (EGF like, fibronectin type III and laminin G domains)

2019-08-01  

Identity

HGNC
EGFLAM
LOCATION
5p13.1
LOCUSID
133584
ALIAS
AGRINL,AGRNL,PIKA

Other Information

Locus ID:

NCBI: 133584
MIM: 617683
HGNC: 26810
Ensembl: ENSG00000164318

Variants:

dbSNP: 133584
ClinVar: 133584
TCGA: ENSG00000164318
COSMIC: EGFLAM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164318ENST00000322350Q63HQ2
ENSG00000164318ENST00000336740Q63HQ2
ENSG00000164318ENST00000354891Q63HQ2
ENSG00000164318ENST00000397202Q63HQ2
ENSG00000164318ENST00000397210Q63HQ2
ENSG00000164318ENST00000504709D6RG24
ENSG00000164318ENST00000506135Q63HQ2
ENSG00000164318ENST00000508131D6RJD2
ENSG00000164318ENST00000514476Q63HQ2

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
retina
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
374905462023Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.0
374905462023Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.0
308296112019EGFLAM correlates with cell proliferation, migration, invasion and poor prognosis in glioblastoma.7
308296112019EGFLAM correlates with cell proliferation, migration, invasion and poor prognosis in glioblastoma.7
283390092017Identification of EGFLAM, SPATC1L and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies.7
283390092017Identification of EGFLAM, SPATC1L and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies.7
197273422009Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice.64
197273422009Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice.64

Citation

Dessen P

EGFLAM (EGF like, fibronectin type III and laminin G domains)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58039/cancer-prone-explorer/case-report-explorer/