KCTD5 (potassium channel tetramerization domain containing 5)

2019-08-01  

Identity

HGNC
KCTD5
LOCATION
16p13.3
LOCUSID
54442
ALIAS
-

Other Information

Locus ID:

NCBI: 54442
MIM: 611285
HGNC: 21423
Ensembl: ENSG00000167977

Variants:

dbSNP: 54442
ClinVar: 54442
TCGA: ENSG00000167977
COSMIC: KCTD5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167977ENST00000301738Q9NXV2
ENSG00000167977ENST00000564195H3BSS5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
387322152024KCTD Proteins Have Redundant Functions in Controlling Cellular Growth.0
387322152024KCTD Proteins Have Redundant Functions in Controlling Cellular Growth.0
349340142022Members of the KCTD family are major regulators of cAMP signaling.13
349340142022Members of the KCTD family are major regulators of cAMP signaling.13
323015522020KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosis.27
330536872020K(+) Channel Tetramerization Domain 5 (KCTD5) Protein Regulates Cell Migration, Focal Adhesion Dynamics and Spreading through Modulation of Ca(2+) Signaling and Rac1 Activity.10
323015522020KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosis.27
330536872020K(+) Channel Tetramerization Domain 5 (KCTD5) Protein Regulates Cell Migration, Focal Adhesion Dynamics and Spreading through Modulation of Ca(2+) Signaling and Rac1 Activity.10
297826462018Cullin3/KCTD5 induces monoubiquitination of ΔNp63α and impairs its activity.7
297826462018Cullin3/KCTD5 induces monoubiquitination of ΔNp63α and impairs its activity.7
285625902017Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.64
285625902017Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.64
261885162015Interactions of cullin3/KCTD5 complexes with both cytoplasmic and nuclear proteins: Evidence for a role in protein stabilization.6
261885162015Interactions of cullin3/KCTD5 complexes with both cytoplasmic and nuclear proteins: Evidence for a role in protein stabilization.6
193614492009Pentameric assembly of potassium channel tetramerization domain-containing protein 5.41

Citation

Dessen P

KCTD5 (potassium channel tetramerization domain containing 5)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58060/teaching-explorer/hgnc