CNKSR3 (CNKSR family member 3)

2019-08-01 Affiliation

Identity

HGNC

CNKSR3

LOCATION

6q25.2

LOCUSID

154043

ALIAS

CNK3,CNK3/IPCEF1,MAGI1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 154043
MIM: 617476
HGNC: 23034
Ensembl: ENSG00000153721

Variants:

dbSNP: 154043
ClinVar: 154043
TCGA: ENSG00000153721
COSMIC: CNKSR3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000153721	ENST00000424998	Q5T4Y8
ENSG00000153721	ENST00000607772	Q6P9H4

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
30019650	2018	Significance of miR-15a-5p and CNKSR3 as Novel Prognostic Biomarkers in Non-Small Cell Lung Cancer.	12
30019650	2018	Significance of miR-15a-5p and CNKSR3 as Novel Prognostic Biomarkers in Non-Small Cell Lung Cancer.	12
28401168	2017	The Association of a Genetic Variant in SCAF8-CNKSR3 with Diabetic Kidney Disease and Diabetic Retinopathy in a Chinese Population.	5
28401168	2017	The Association of a Genetic Variant in SCAF8-CNKSR3 with Diabetic Kidney Disease and Diabetic Retinopathy in a Chinese Population.	5
23357503	2013	Single nucleotide polymorphism array analysis of uveal melanomas reveals that amplification of CNKSR3 is correlated with improved patient survival.	13
23357503	2013	Single nucleotide polymorphism array analysis of uveal melanomas reveals that amplification of CNKSR3 is correlated with improved patient survival.	13
22085542	2012	CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration.	16
22457146	2012	Differential gene expression profile in PBMCs from subjects with AERD and ATA: a gene marker for AERD.	9
22851176	2012	Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex.	12
22085542	2012	CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration.	16
22457146	2012	Differential gene expression profile in PBMCs from subjects with AERD and ATA: a gene marker for AERD.	9
22851176	2012	Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex.	12
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
19567370	2009	Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel.	23

Citation

Dessen P

CNKSR3 (CNKSR family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2019-08-01

Online version: http://atlasgeneticsoncology.org/gene/58090/teaching-explorer/js/lib/favicon/tumors-explorer/