AGPAT4 (1-acylglycerol-3-phosphate O-acyltransferase 4)

2014-11-01  

Identity

HGNC
LOCATION
6q26
LOCUSID
ALIAS
1-AGPAT4,LPAAT-delta,dJ473J16.2
FUSION GENES

Other Information

Locus ID:

NCBI: 56895
MIM: 614795
HGNC: 20885
Ensembl: ENSG00000026652

Variants:

dbSNP: 56895
ClinVar: 56895
TCGA: ENSG00000026652
COSMIC: AGPAT4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000026652ENST00000320285Q9NRZ5
ENSG00000026652ENST00000366905Q5TEE8
ENSG00000026652ENST00000366911Q6AI25
ENSG00000026652ENST00000436279G3XAF1
ENSG00000026652ENST00000437165H0Y5R3

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Glycerolipid metabolismKEGGko00561
Glycerophospholipid metabolismKEGGko00564
Glycerolipid metabolismKEGGhsa00561
Glycerophospholipid metabolismKEGGhsa00564
Metabolic pathwaysKEGGhsa01100
Triacylglycerol biosynthesisKEGGhsa_M00089
Triacylglycerol biosynthesisKEGGM00089
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Synthesis of PAREACTOMER-HSA-1483166
Phospholipase D signaling pathwayKEGGko04072
Phospholipase D signaling pathwayKEGGhsa04072

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
322960172020The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.29
322960172020The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.29
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

AGPAT4 (1-acylglycerol-3-phosphate O-acyltransferase 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60205/gene-explorer/favicon/cancer-prone-explorer/