CD300E (CD300e molecule)

2014-11-01  

Identity

HGNC
CD300E
LOCATION
17q25.1
LOCUSID
342510
ALIAS
CD300LE,CLM-2,CLM2,CMRF35-A5,IREM-2,IREM2,PIgR-2,PIgR2

Other Information

Locus ID:

NCBI: 342510
MIM: 609801
HGNC: 28874
Ensembl: ENSG00000186407

Variants:

dbSNP: 342510
ClinVar: 342510
TCGA: ENSG00000186407
COSMIC: CD300E

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186407ENST00000392619Q496F6
ENSG00000186407ENST00000412268C9JDD2

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933
Innate Immune SystemREACTOMER-HSA-168249
DAP12 interactionsREACTOMER-HSA-2172127

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
330205632020The immune receptor CD300e negatively regulates T cell activation by impairing the STAT1-dependent antigen presentation.13
330205632020The immune receptor CD300e negatively regulates T cell activation by impairing the STAT1-dependent antigen presentation.13
280052672017Human gingiva transcriptome during wound healing.14
280052672017Human gingiva transcriptome during wound healing.14
230728612013CD300 molecule regulation of human dendritic cell functions.12
230728612013CD300 molecule regulation of human dendritic cell functions.12
202009532010Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study.27
202009532010Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study.27
155571622004Molecular characterization of a novel immune receptor restricted to the monocytic lineage.25
155571622004Molecular characterization of a novel immune receptor restricted to the monocytic lineage.25

Citation

Dessen P

CD300E (CD300e molecule)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61620/js/lib/teaching-explorer/