CDX4 (caudal type homeobox 4)

2014-11-01  

Identity

HGNC
CDX4
LOCATION
Xq13.2
LOCUSID
1046

Other Information

Locus ID:

NCBI: 1046
MIM: 300025
HGNC: 1808
Ensembl: ENSG00000131264

Variants:

dbSNP: 1046
ClinVar: 1046
TCGA: ENSG00000131264
COSMIC: CDX4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131264ENST00000373514O14627

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
284084652017Human definitive hematopoietic specification from pluripotent stem cells is regulated by mesodermal expression of CDX4.16
284084652017Human definitive hematopoietic specification from pluripotent stem cells is regulated by mesodermal expression of CDX4.16
227216482012Ectopic expression of CDX4 in human mesenchymal stem cells does not affect HOX gene expression or induce hematopoietic reprogramming.0
230382462012β-Catenin activates the HOXA10 and CDX4 genes in myeloid progenitor cells.10
227216482012Ectopic expression of CDX4 in human mesenchymal stem cells does not affect HOX gene expression or induce hematopoietic reprogramming.0
230382462012β-Catenin activates the HOXA10 and CDX4 genes in myeloid progenitor cells.10
214712172011HoxA10 activates CDX4 transcription and Cdx4 activates HOXA10 transcription in myeloid cells.17
215184752011[Expression and clinical significance of caudal type homeobox transcription factor-2 in adult acute lymphocytic leukemia].1
214712172011HoxA10 activates CDX4 transcription and Cdx4 activates HOXA10 transcription in myeloid cells.17
215184752011[Expression and clinical significance of caudal type homeobox transcription factor-2 in adult acute lymphocytic leukemia].1

Citation

Dessen P

CDX4 (caudal type homeobox 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61670/css/gene-explorer/