DENND1C (DENN domain containing 1C)

2014-11-01  

Identity

HGNC
DENND1C
LOCATION
19p13.3
LOCUSID
79958
ALIAS
FAM31C
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79958
MIM: 613634
HGNC: 26225
Ensembl: ENSG00000205744

Variants:

dbSNP: 79958
ClinVar: 79958
TCGA: ENSG00000205744
COSMIC: DENND1C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205744ENST00000381480Q8IV53
ENSG00000205744ENST00000543576Q8IV53
ENSG00000205744ENST00000586046K7EM30
ENSG00000205744ENST00000588421K7EM80
ENSG00000205744ENST00000590173K7ENM0
ENSG00000205744ENST00000590473K7EMN9
ENSG00000205744ENST00000590867K7EKL5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
220727932012Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeleton.33
220727932012Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeleton.33

Citation

Dessen P

DENND1C (DENN domain containing 1C)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62428/favicon/case-report-explorer/