GLTP (glycolipid transfer protein)

2014-11-01  

Identity

HGNC
GLTP
LOCATION
12q24.11
LOCUSID
51228
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51228
MIM: 608949
HGNC: 24867
Ensembl: ENSG00000139433

Variants:

dbSNP: 51228
ClinVar: 51228
TCGA: ENSG00000139433
COSMIC: GLTP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139433ENST00000318348Q9NZD2
ENSG00000139433ENST00000318348A0A024RBI7
ENSG00000139433ENST00000536390F5GZ49
ENSG00000139433ENST00000537066F5GZ49
ENSG00000139433ENST00000540772H0YFS9
ENSG00000139433ENST00000544393F5H0U5
ENSG00000139433ENST00000617457F5GZ49

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Sphingolipid metabolismREACTOMER-HSA-428157
Glycosphingolipid metabolismREACTOMER-HSA-1660662

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369249442023Glycolipid transfer protein knockout disrupts vesicle trafficking to the plasma membrane.3
371918542023Role of Gltp in Maturation of Oligodendrocytes Under the Regulation of Nkx2.2.0
369249442023Glycolipid transfer protein knockout disrupts vesicle trafficking to the plasma membrane.3
371918542023Role of Gltp in Maturation of Oligodendrocytes Under the Regulation of Nkx2.2.0
323395542020Emerging roles for human glycolipid transfer protein superfamily members in the regulation of autophagy, inflammation, and cell death.16
323395542020Emerging roles for human glycolipid transfer protein superfamily members in the regulation of autophagy, inflammation, and cell death.16
295324062019MicroRNA 196B Regulates HOXA5, HOXB6 and GLTP Expression Levels in Colorectal Cancer Cells.9
295324062019MicroRNA 196B Regulates HOXA5, HOXB6 and GLTP Expression Levels in Colorectal Cancer Cells.9
302061202018Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family.6
302061202018Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family.6
274126752016Synthesis of a novel photoactivatable glucosylceramide cross-linker.2
274126752016Synthesis of a novel photoactivatable glucosylceramide cross-linker.2
248246062014Alternation in the glycolipid transfer protein expression causes changes in the cellular lipidome.12
248246062014Alternation in the glycolipid transfer protein expression causes changes in the cellular lipidome.12
235196692013Structural insights into lipid-dependent reversible dimerization of human GLTP.8

Citation

Dessen P

GLTP (glycolipid transfer protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63833/js/gene-fusions-explorer/