GPR180 (G protein-coupled receptor 180)

2014-11-01  

Identity

HGNC
GPR180
LOCATION
13q32.1
LOCUSID
160897
ALIAS
ITR
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 160897
MIM: 607787
HGNC: 28899
Ensembl: ENSG00000152749

Variants:

dbSNP: 160897
ClinVar: 160897
TCGA: ENSG00000152749
COSMIC: GPR180

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000152749ENST00000376958Q86V85

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
367260162023Lack of GPR180 ameliorates hepatic lipid depot via downregulation of mTORC1 signaling.1
367260162023Lack of GPR180 ameliorates hepatic lipid depot via downregulation of mTORC1 signaling.1
348802172021GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1.10
348802172021GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1.10
322000022020Microcoria due to first duplication of 13q32.1 including the GPR180 gene and maternal mosaicism.4
322000022020Microcoria due to first duplication of 13q32.1 including the GPR180 gene and maternal mosaicism.4
257729372015Submicroscopic deletions at 13q32.1 cause congenital microcoria.4
257729372015Submicroscopic deletions at 13q32.1 cause congenital microcoria.4
127307182003High-density SNP map of human ITR, a gene associated with vascular remodeling.4
127307182003High-density SNP map of human ITR, a gene associated with vascular remodeling.4

Citation

Dessen P

GPR180 (G protein-coupled receptor 180)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63981/deep-insight-explorer/js/lib/case-report-explorer/