HSH2D (hematopoietic SH2 domain containing)

2014-11-01  

Identity

HGNC
HSH2D
LOCATION
19p13.11
LOCUSID
84941
ALIAS
ALX,HSH2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84941
MIM: 608349
HGNC: 24920
Ensembl: ENSG00000196684

Variants:

dbSNP: 84941
ClinVar: 84941
TCGA: ENSG00000196684
COSMIC: HSH2D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196684ENST00000586872K7ES08
ENSG00000196684ENST00000591154K7ER77
ENSG00000196684ENST00000593031K7EP18
ENSG00000196684ENST00000613195A0A087X0V9
ENSG00000196684ENST00000613986Q96JZ2
ENSG00000196684ENST00000616070A0A087WT88
ENSG00000196684ENST00000616645Q96JZ2

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
330002782020HSH2D contributes to methotrexate resistance in human T‑cell acute lymphoblastic leukaemia.0
330002782020HSH2D contributes to methotrexate resistance in human T‑cell acute lymphoblastic leukaemia.0
278604532017Targeting the D Series Resolvin Receptor System for the Treatment of Osteoarthritis Pain.26
278604532017Targeting the D Series Resolvin Receptor System for the Treatment of Osteoarthritis Pain.26
262480462015Differential regulation of monocytic expression of leukotriene and lipoxin receptors.5
262480462015Differential regulation of monocytic expression of leukotriene and lipoxin receptors.5
241667362014Lipoxin A₄ modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism.46
241667362014Lipoxin A₄ modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism.46
200806362010Resolvin D1 binds human phagocytes with evidence for proresolving receptors.365
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
204713662010Phosphorylation at serine 318 is not required for inhibition of T cell activation by ALX.1
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
200806362010Resolvin D1 binds human phagocytes with evidence for proresolving receptors.365
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
204713662010Phosphorylation at serine 318 is not required for inhibition of T cell activation by ALX.1

Citation

Dessen P

HSH2D (hematopoietic SH2 domain containing)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64450/meetings/