MDFIC (MyoD family inhibitor domain containing)

2014-11-01 Affiliation

Identity

HGNC

MDFIC

LOCATION

7q31.1

LOCUSID

29969

ALIAS

HIC,MDFIC1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 29969
MIM: 614511
HGNC: 28870
Ensembl: ENSG00000135272

Variants:

dbSNP: 29969
ClinVar: 29969
TCGA: ENSG00000135272
COSMIC: MDFIC

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000135272	ENST00000257724	J3KN13
ENSG00000135272	ENST00000393486	Q9P1T7
ENSG00000135272	ENST00000423503	C9J104
ENSG00000135272	ENST00000427207	H7BZY3
ENSG00000135272	ENST00000431629	H7C4B9
ENSG00000135272	ENST00000448022	C9J104
ENSG00000135272	ENST00000498196	C9J784

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
37590348	2023	MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels.	6
37590348	2023	MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels.	6
35235341	2022	Pathogenic variants in MDFIC cause recessive central conducting lymphatic anomaly with lymphedema.	12
35235341	2022	Pathogenic variants in MDFIC cause recessive central conducting lymphatic anomaly with lymphedema.	12
32457453	2020	Opposite Roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer.	17
32457453	2020	Opposite Roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer.	17
28223352	2017	Cross-talk between the glucocorticoid receptor and MyoD family inhibitor domain-containing protein provides a new mechanism for generating tissue-specific responses to glucocorticoids.	14
28223352	2017	Cross-talk between the glucocorticoid receptor and MyoD family inhibitor domain-containing protein provides a new mechanism for generating tissue-specific responses to glucocorticoids.	14
26469549	2015	I-mfa domain proteins specifically interact with HTLV-1 Tax and repress its transactivating functions.	9
26469549	2015	I-mfa domain proteins specifically interact with HTLV-1 Tax and repress its transactivating functions.	9
21401918	2011	Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: novel insights into the regulation of Rev nuclear import.	15
21401918	2011	Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: novel insights into the regulation of Rev nuclear import.	15
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20417616	2010	Human I-mfa domain proteins specifically interact with KSHV LANA and affect its regulation of Wnt signaling-dependent transcription.	15
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78

Citation

Dessen P

MDFIC (MyoD family inhibitor domain containing)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68859/favicon/gene-fusions-explorer/