PHOSPHO1 (phosphoethanolamine/phosphocholine phosphatase 1)

2014-11-01  

Identity

HGNC
PHOSPHO1
LOCATION
17q21.32
LOCUSID
162466
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 162466
HGNC: 16815
Ensembl: ENSG00000173868

Variants:

dbSNP: 162466
ClinVar: 162466
TCGA: ENSG00000173868
COSMIC: PHOSPHO1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173868ENST00000310544Q8TCT1
ENSG00000173868ENST00000413580Q8TCT1
ENSG00000173868ENST00000503902D6RB58
ENSG00000173868ENST00000511066D6RHH9
ENSG00000173868ENST00000512250D6RIT6
ENSG00000173868ENST00000514112Q8TCT1
ENSG00000173868ENST00000574638I3L4N1

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Glycerophospholipid metabolismKEGGko00564
Glycerophospholipid metabolismKEGGhsa00564
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Synthesis of PEREACTOMER-HSA-1483213
Synthesis of PCREACTOMER-HSA-1483191

References

Pubmed IDYearTitleCitations
359436802022PHOSPHO1 Serves as a Key Metabolism-Related Biomarker in the Tumorigenesis of Diffuse Large B-cell Lymphoma.1
359436802022PHOSPHO1 Serves as a Key Metabolism-Related Biomarker in the Tumorigenesis of Diffuse Large B-cell Lymphoma.1
271487722016DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk.92
281731502016Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study.46
271487722016DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk.92
281731502016Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach. The REGICOR study.46
245339432014Role of bone-type tissue-nonspecific alkaline phosphatase and PHOSPO1 in vascular calcification.18
245339432014Role of bone-type tissue-nonspecific alkaline phosphatase and PHOSPO1 in vascular calcification.18
194532612009High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.23
194532612009High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.23
184719962008Identification of a novel splice variant of the haloacid dehalogenase: PHOSPHO1.2
184719962008Identification of a novel splice variant of the haloacid dehalogenase: PHOSPHO1.2
160544482005Probing the substrate specificities of human PHOSPHO1 and PHOSPHO2.18
160544482005Probing the substrate specificities of human PHOSPHO1 and PHOSPHO2.18

Citation

Dessen P

PHOSPHO1 (phosphoethanolamine/phosphocholine phosphatase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71891/gene-explorer/haematological-explorer/