PSORS1C3 (psoriasis susceptibility 1 candidate 3)

2014-11-01 Affiliation

Identity

HGNC

PSORS1C3

LOCATION

6p21.33

LOCUSID

100130889

ALIAS

NCRNA00196

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 100130889
MIM: 618690
HGNC: 17203

Variants:

dbSNP: 100130889
ClinVar: 100130889
COSMIC: PSORS1C3

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

PharmGKB

Entity ID	Name	Type	Evidence	Association	PD	PMIDs
PA166120929	severe cutaneous adverse reactions	Disease	ClinicalAnnotation	associated	PD	21801394
PA444059	Epidermal Necrolysis, Toxic	Disease	ClinicalAnnotation	associated	PD	21801394
PA445738	Stevens-Johnson Syndrome	Disease	ClinicalAnnotation	associated	PD	21801394
PA448320	allopurinol	Chemical	ClinicalAnnotation	associated	PD	21801394

References

Pubmed ID	Year	Title	Citations
31182783	2019	lncRNA PSORS1C3 is regulated by glucocorticoids and fine-tunes OCT4 expression in non-pluripotent cells.	12
31182783	2019	lncRNA PSORS1C3 is regulated by glucocorticoids and fine-tunes OCT4 expression in non-pluripotent cells.	12
29589160	2018	HLA-C*06:02-independent, gender-related association of PSORS1C3 and PSORS1C1/CDSN single-nucleotide polymorphisms with risk and severity of psoriasis.	17
29589160	2018	HLA-C*06:02-independent, gender-related association of PSORS1C3 and PSORS1C1/CDSN single-nucleotide polymorphisms with risk and severity of psoriasis.	17
28045465	2017	Methylomic profiling of cortex samples from completed suicide cases implicates a role for PSORS1C3 in major depression and suicide.	38
28045465	2017	Methylomic profiling of cortex samples from completed suicide cases implicates a role for PSORS1C3 in major depression and suicide.	38
16965413	2006	Psoriasis vulgaris in Chinese individuals is associated with PSORS1C3 and CDSN genes.	16
16965413	2006	Psoriasis vulgaris in Chinese individuals is associated with PSORS1C3 and CDSN genes.	16
15848982	2005	HLA-Cw*0602 associates more strongly to psoriasis in the Swedish population than variants of the novel 6p21.3 gene PSORS1C3.	20
15848982	2005	HLA-Cw*0602 associates more strongly to psoriasis in the Swedish population than variants of the novel 6p21.3 gene PSORS1C3.	20

Citation

Dessen P

PSORS1C3 (psoriasis susceptibility 1 candidate 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72361/js/lib/deep-insight-explorer/welcome