RIC8B (RIC8 guanine nucleotide exchange factor B)

2014-11-01  

Identity

HGNC
LOCATION
12q23.3
LOCUSID
ALIAS
RIC8,hSyn
FUSION GENES

Other Information

Locus ID:

NCBI: 55188
MIM: 609147
HGNC: 25555
Ensembl: ENSG00000111785

Variants:

dbSNP: 55188
ClinVar: 55188
TCGA: ENSG00000111785
COSMIC: RIC8B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111785ENST00000355478Q9NVN3
ENSG00000111785ENST00000392837B7WPL0
ENSG00000111785ENST00000392839Q9NVN3
ENSG00000111785ENST00000462949Q9NVN3
ENSG00000111785ENST00000462949A0A024RBG9
ENSG00000111785ENST00000470960Q9NVN3
ENSG00000111785ENST00000546449J3QRA4
ENSG00000111785ENST00000548914H0YHS3
ENSG00000111785ENST00000549643F8VR30
ENSG00000111785ENST00000550215F8VSN5
ENSG00000111785ENST00000552619F8VY51

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
267294112016The CREB Transcription Factor Controls Transcriptional Activity of the Human RIC8B Gene.1
269661862016ARMS/Kidins220 and synembryn-B levels regulate NGF-mediated secretion.4
267294112016The CREB Transcription Factor Controls Transcriptional Activity of the Human RIC8B Gene.1
269661862016ARMS/Kidins220 and synembryn-B levels regulate NGF-mediated secretion.4
201339392010Ric-8B stabilizes the alpha subunit of stimulatory G protein by inhibiting its ubiquitination.26
201339392010Ric-8B stabilizes the alpha subunit of stimulatory G protein by inhibiting its ubiquitination.26
126526422003Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.27
126526422003Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.27

Citation

Dessen P

RIC8B (RIC8 guanine nucleotide exchange factor B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72641/css/favicon/manifest.json