TAF3 (TATA-box binding protein associated factor 3)

2014-11-01 Affiliation

Identity

HGNC

TAF3

LOCATION

10p14

LOCUSID

83860

ALIAS

TAF140,TAFII-140,TAFII140

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 83860
MIM: 606576
HGNC: 17303
Ensembl: ENSG00000165632

Variants:

dbSNP: 83860
ClinVar: 83860
TCGA: ENSG00000165632
COSMIC: TAF3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000165632	ENST00000344293	Q5VWG9

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Basal transcription factors	KEGG	ko03022
Basal transcription factors	KEGG	hsa03022
Herpes simplex infection	KEGG	ko05168
Herpes simplex infection	KEGG	hsa05168
Disease	REACTOME	R-HSA-1643685
Infectious disease	REACTOME	R-HSA-5663205
HIV Infection	REACTOME	R-HSA-162906
HIV Life Cycle	REACTOME	R-HSA-162587
Late Phase of HIV Life Cycle	REACTOME	R-HSA-162599
Transcription of the HIV genome	REACTOME	R-HSA-167172
HIV Transcription Initiation	REACTOME	R-HSA-167161
RNA Polymerase II HIV Promoter Escape	REACTOME	R-HSA-167162
Gene Expression	REACTOME	R-HSA-74160
Generic Transcription Pathway	REACTOME	R-HSA-212436
Transcriptional Regulation by TP53	REACTOME	R-HSA-3700989
RNA Polymerase II Transcription	REACTOME	R-HSA-73857
RNA Polymerase II Pre-transcription Events	REACTOME	R-HSA-674695
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	REACTOME	R-HSA-73779
RNA Polymerase II Transcription Initiation And Promoter Clearance	REACTOME	R-HSA-76042
RNA Polymerase II Transcription Initiation	REACTOME	R-HSA-75953
RNA Polymerase II Promoter Escape	REACTOME	R-HSA-73776
Regulation of TP53 Activity	REACTOME	R-HSA-5633007
Regulation of TP53 Activity through Phosphorylation	REACTOME	R-HSA-6804756

References

Pubmed ID	Year	Title	Citations
23452851	2013	H3K4me3 interactions with TAF3 regulate preinitiation complex assembly and selective gene activation.	221
23935956	2013	Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans.	8
23452851	2013	H3K4me3 interactions with TAF3 regulate preinitiation complex assembly and selective gene activation.	221
23935956	2013	Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans.	8
21884934	2011	Control of embryonic stem cell lineage commitment by core promoter factor, TAF3.	110
21884934	2011	Control of embryonic stem cell lineage commitment by core promoter factor, TAF3.	110
20808825	2010	Novel association strategy with copy number variation for identifying new risk Loci of human diseases.	14
20808825	2010	Novel association strategy with copy number variation for identifying new risk Loci of human diseases.	14
19023099	2009	Gene variants associated with ischemic stroke: the cardiovascular health study.	20
19240061	2009	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	94
19023099	2009	Gene variants associated with ischemic stroke: the cardiovascular health study.	20
19240061	2009	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	94
17975119	2008	Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.	77
18549481	2008	TATA binding protein associated factor 3 (TAF3) interacts with p53 and inhibits its function.	13
17975119	2008	Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.	77

Citation

Dessen P

TAF3 (TATA-box binding protein associated factor 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74469/gene-explorer/favicon/teaching-explorer/