ZNHIT2 (zinc finger HIT-type containing 2)

2014-11-01  

Identity

HGNC
ZNHIT2
LOCATION
11q13.1
LOCUSID
741
ALIAS
C11orf5,FON

Other Information

Locus ID:

NCBI: 741
MIM: 604575
HGNC: 1177
Ensembl: ENSG00000174276

Variants:

dbSNP: 741
ClinVar: 741
TCGA: ENSG00000174276
COSMIC: ZNHIT2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174276ENST00000310597Q9UHR6
ENSG00000174276ENST00000528598E9PQB8

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
285610262017R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.57
285610262017R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.57
176565772007Solution structure of the zinc finger HIT domain in protein FON.8
176565772007Solution structure of the zinc finger HIT domain in protein FON.8

Citation

Dessen P

ZNHIT2 (zinc finger HIT-type containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/76466/cancer-prone-explorer/case-report-explorer/teaching-explorer/