ZXDC (ZXD family zinc finger C)

2014-11-01 Affiliation

Identity

HGNC

ZXDC

LOCATION

3q21.3

LOCUSID

79364

ALIAS

ZXDL

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 79364
MIM: 615746
HGNC: 28160
Ensembl: ENSG00000070476

Variants:

dbSNP: 79364
ClinVar: 79364
TCGA: ENSG00000070476
COSMIC: ZXDC

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000070476	ENST00000336332	Q2QGD7
ENSG00000070476	ENST00000389709	Q2QGD7
ENSG00000070476	ENST00000515545	H0YAA9

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
36497052	2022	CircZXDC Promotes Vascular Smooth Muscle Cell Transdifferentiation via Regulating miRNA-125a-3p/ABCC6 in Moyamoya Disease.	5
36497052	2022	CircZXDC Promotes Vascular Smooth Muscle Cell Transdifferentiation via Regulating miRNA-125a-3p/ABCC6 in Moyamoya Disease.	5
28993696	2017	An eQTL variant of ZXDC is associated with IFN-γ production following Mycobacterium tuberculosis antigen-specific stimulation.	3
28993696	2017	An eQTL variant of ZXDC is associated with IFN-γ production following Mycobacterium tuberculosis antigen-specific stimulation.	3
23954399	2013	The zinc finger transcription factor ZXDC activates CCL2 gene expression by opposing BCL6-mediated repression.	8
23954399	2013	The zinc finger transcription factor ZXDC activates CCL2 gene expression by opposing BCL6-mediated repression.	8
19777325	2010	An N- and C-terminal truncated isoform of zinc finger X-linked duplicated C protein represses MHC class II transcription.	3
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
19777325	2010	An N- and C-terminal truncated isoform of zinc finger X-linked duplicated C protein represses MHC class II transcription.	3
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
16600381	2007	ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription.	12
17493635	2007	The zinc finger proteins ZXDA and ZXDC form a complex that binds CIITA and regulates MHC II gene transcription.	14
17696781	2007	Sumoylation of the zinc finger protein ZXDC enhances the function of its transcriptional activation domain.	5
16600381	2007	ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription.	12
17493635	2007	The zinc finger proteins ZXDA and ZXDC form a complex that binds CIITA and regulates MHC II gene transcription.	14

Citation

Dessen P

ZXDC (ZXD family zinc finger C)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/76516/gene-fusions/humanGenome