Near haploid acute lymphoblastic leukaemia

1999-06-01   Barbara Gibbons 

1.NE London Regional Cytogenetics Laboratory 2nd Floor, Queen Square House Institute of Neurology Queen Square London WC1N 3BG, UK

Clinics and Pathology

Disease

acute lymphoblastic leukemia (ALL)

Phenotype stem cell origin

B precursor ALL

Epidemiology

a rare type of leukaemia; near-haploid patients tend to be children or teenagers; slight excess of females

Prognosis

generally short complete remission duration and poor prognosis, although long survivors have been reported

Cytogenetics

Cytogenetics morphological

near haploidy is usually defined as 50 hyperdiploid ALL; the distinction is important as near-haploidy defines a rare type of childhood ALL associated with short median complete remission duration and poor prognosis

Additional anomalies

occasional structural chromosome abnormality

Bibliography

Pubmed IDLast YearTitleAuthors

Citation

Barbara Gibbons

Near haploid acute lymphoblastic leukaemia

Atlas Genet Cytogenet Oncol Haematol. 1999-06-01

Online version: http://atlasgeneticsoncology.org/haematological/1145/tumors-explorer/