t(12;17)(p11;q11) in AML

2006-11-01   David Betts 

1.Department of Oncology, University Childrens Hospital, Steinwiesstr. 75, CH-8032 Zò_rich, Switzerland

Clinics and Pathology

Disease

Acute myeloid leukaemia (AML)

Note

The appearance of the translocation may resemble the rare non-random t(12;17)(p13;q11-21) associated with ALL.

Epidemiology

Very rare translocation reported in three adults and one child with secondary AML following an ALL. The four published cases have been female.

Prognosis

Insufficient data to indicate a prognostic significance.

Genes Involved and Proteins

Note
No report of any molecular or FISH data to elucidate exact breakpoint or genes.

Bibliography

Pubmed IDLast YearTitleAuthors

Citation

David Betts

t(12;17)(p11;q11) in AML

Atlas Genet Cytogenet Oncol Haematol. 2006-11-01

Online version: http://atlasgeneticsoncology.org/haematological/1437/favicon/css/favicon/manifest.json