t(1;14)(p33;q11) TRD/TAL1

2018-01-01   Philippe Dessen  , Jean-Loup Huret  

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes Involved and Proteins

Gene name
TRD
Location
14q11.2
Gene name
TAL1
Location
1p33

Article Bibliography

Pubmed IDLast YearTitleAuthors
19645811990Two distinct mechanisms for the SCL gene activation in the t(1;14) translocation of T-cell leukemias.Bernard O et al
23030351990The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein.Chen Q et al
27403411989Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma.Finger LR et al
84123121993Characterization of translocation t(1;14)(p32;q11) in a T and in a B acute leukemia.Bernard O et al

Summary

Fusion gene

TRD/TAL1 TRD (14q11.2) TAL1 (1p33)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Citation

Philippe Dessen ; Jean-Loup Huret

t(1;14)(p33;q11) TRD/TAL1

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/3297/cancer-prone-explorer/js/template.js