t(7;22)(q34;q12) EWSR1/CREB3L2

0000-00-00   Jean-Loup Huret  , Philippe Dessen  

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

EWSR1

Location

22q12.2

Gene name

CREB3L2

Location

7q33

Highly cited references

Pubmed IDYearTitleCitations
286489412017Low-grade fibromyxoid sarcoma: Clinical, morphologic and genetic features.15
327694312021Sclerosing Epithelioid Fibrosarcoma: A Distinct Sarcoma With Aggressive Features.4
316751342020Clinical and molecular characterization of primary sclerosing epithelioid fibrosarcoma of bone and review of the literature.2
341592432021First description of hematogenously metastasized sclerosing epithelioid fibrosarcoma arising in the uterine cervix.0

Article Bibliography

Pubmed IDLast YearTitleAuthors
252311342015A genetic dichotomy between pure sclerosing epithelioid fibrosarcoma (SEF) and hybrid SEF/low-grade fibromyxoid sarcoma: a pathologic and molecular study of 18 cases.Prieto-Granada C et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(7;22)(q34;q12) EWSR1/CREB3L2

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/107513/gene-explorer/case-report-explorer/