Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 1
2005-01-01 Kavita S. Reddy, Kathy Richkind AffiliationGenzyme Genetics, Orange, CA. [email protected]
Previous history
Preleukaemia
-
Malignant disease
Breast infiltrating ductal carcinoma treated with radiation and tamoxifen.
Clinics case report
Age
57 yrs
Sex
F
Liver
-
Spleen
-
Lymph nodes
-
Cns involv
-
Blood data
Wbc
3.8
Hb
11.4
Platelets
160
Cyto path
Precise diagnosis
Myelodysplastic syndrome (MDS): refractory anaemia
Survival data
Treatment
Maintenance therapy for MDS patient declined bone marrow transplantation (BMT)
Relapse
-
Status
A
Survival
42 +
Karyotype
Sample
BM
Culture time
24/48 unstimulated cultures
Banding
G-banding
Results
46,X,t(X;20)(q13;q13.3)[5]/46,XX[15]
Images
Fig. 1. Partial karyotypes of the translocation t(X;20)(q13;q13.3) for cases 1ï4 (top to bottom). Arrows indicate the derivatives 20 and X.
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 7627929 | 1995 | Characterization by chromosome painting of balanced and unbalanced X chromosome translocations in myelodysplastic syndromes. | Michaux L et al |
| 12606138 | 2003 | Translocation (X;20)(q13.1;q13.3) as a primary chromosomal finding in two patients with myelocytic disorders. | Gray BA et al |
| 15676151 | 2005 | Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders. | Reddy KS et al |
Citation
Kavita S. Reddy, Kathy Richkind
Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders: case 1
Atlas Genet Cytogenet Oncol Haematol. 2005-01-01
Online version: http://atlasgeneticsoncology.org/case-report/208807/translocation-(x
