t(8;13)(p12;q12) in an atypical chronic myeloid leukaemia case
2006-12-01 Valeria AS De Melo, Alistair G Reid AffiliationLeukaemia Cytogenetics Unit, G Block Room G124, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK
Clinics case report
Age
43 yrs
Sex
M
Spleen
-
Lymph nodes
+
Blood data
Wbc
9.8
Hb
11.5
Platelets
28
Cyto path
Precise diagnosis
Atypical chronic myeloid leukaemia
Survival data
Date diagnosis
02-1992
Treatment
Chemo/Radiation/bone marrow transplantation
Complete remission
+
Treatment relat death
+
Relapse
-
Status
D
Date last follow
06-1994
Survival
28
Karyotype
Sample
Bone marrow
Culture time
CM FUDR 48 h
Banding
G-banding
Results
46,XY,t(8;13)(p12;q12)[8]/46,XY[2]
Images
Partial karyotype showing the t(8;13)(p12;q12) - G-banding
Comments section
Comments
Eight of the metaphases examined showed a translocation between chromosomes 8 and 13. There was no evidence of a Philadelphia translocation. The t(8;13) is usually found in myeloproliferative syndromes with FGFR1 involvement and a poor prognosis
Bibliography
No bibliography items were found for this article.
Citation
Valeria AS De Melo, Alistair G Reid
t(8;13)(p12;q12) in an atypical chronic myeloid leukaemia case
Atlas Genet Cytogenet Oncol Haematol. 2006-12-01
Online version: http://atlasgeneticsoncology.org/case-report/208816/t(8
