BTG1 (BTG anti-proliferation factor 1)

2003-02-01  

Identity

HGNC
BTG1
LOCATION
12q21.33
LOCUSID
694
ALIAS
APRO2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 694
MIM: 109580
HGNC: 1130
Ensembl: ENSG00000133639

Variants:

dbSNP: 694
ClinVar: 694
TCGA: ENSG00000133639
COSMIC: BTG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000133639ENST00000256015P62324
ENSG00000133639ENST00000256015Q6IBC8

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018

References

Pubmed IDYearTitleCitations
382541532024The predictive value of BTG1 for the response of newly diagnosed acute myeloid leukemia to decitabine.0
382541532024The predictive value of BTG1 for the response of newly diagnosed acute myeloid leukemia to decitabine.0
363751192023BTG1 inactivation drives lymphomagenesis and promotes lymphoma dissemination through activation of BCAR1.3
366569332023BTG1 mutation yields supercompetitive B cells primed for malignant transformation.9
363751192023BTG1 inactivation drives lymphomagenesis and promotes lymphoma dissemination through activation of BCAR1.3
366569332023BTG1 mutation yields supercompetitive B cells primed for malignant transformation.9
358804342022Emerging role of anti-proliferative protein BTG1 and BTG2.9
358804342022Emerging role of anti-proliferative protein BTG1 and BTG2.9
330214112021Frequent loss of BTG1 activity and impaired interactions with the Caf1 subunit of the Ccr4-Not deadenylase in non-Hodgkin lymphoma.6
337601192021Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA.9
330214112021Frequent loss of BTG1 activity and impaired interactions with the Caf1 subunit of the Ccr4-Not deadenylase in non-Hodgkin lymphoma.6
337601192021Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA.9
319165202020Expression of B Cell Translocation Gene 1 Protein in Colon Carcinoma and its Clinical Significance.6
321666692020Identification of BTG1 Status in Solid Cancer for Future Researches Using a System Review and Meta-analysis.1
324572822020Prognostic significance of low expression of B-cell translocation gene 1 (BTG 1) in skin squamous cell carcinoma.2

Citation

Dessen P

BTG1 (BTG anti-proliferation factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/110/btg1-(btg-anti-proliferation-factor-1)