H1-1 (H1.1 linker histone, cluster member)

2004-05-01  

Identity

HGNC
LOCATION
6p22.2
LOCUSID
ALIAS
H1.1,H1A,H1F1,HIST1,HIST1H1A

Other Information

Locus ID:

NCBI: 3024
MIM: 142709
HGNC: 4715
Ensembl: ENSG00000124610

Variants:

dbSNP: 3024
ClinVar: 3024
TCGA: ENSG00000124610
COSMIC: H1-1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124610ENST00000244573Q02539

Pathways

PathwaySourceExternal ID
Programmed Cell DeathREACTOMER-HSA-5357801
ApoptosisREACTOMER-HSA-109581
Apoptotic execution phaseREACTOMER-HSA-75153
Apoptosis induced DNA fragmentationREACTOMER-HSA-140342
Activation of DNA fragmentation factorREACTOMER-HSA-211227
Cellular responses to stressREACTOMER-HSA-2262752
Cellular SenescenceREACTOMER-HSA-2559583
DNA Damage/Telomere Stress Induced SenescenceREACTOMER-HSA-2559586
Formation of Senescence-Associated Heterochromatin Foci (SAHF)REACTOMER-HSA-2559584

References

Pubmed IDYearTitleCitations
346638562021Brain age estimation at tract group level and its association with daily life measures, cardiac risk factors and genetic variants.9
346638562021Brain age estimation at tract group level and its association with daily life measures, cardiac risk factors and genetic variants.9
283618542017Anti-histone H1 IgGs possess proliferative activity towards human T-leukaemia CEM cells.0
283618542017Anti-histone H1 IgGs possess proliferative activity towards human T-leukaemia CEM cells.0
254821322015PcG methylation of the HIST1 cluster defines an epigenetic marker of acute myeloid leukemia.5
261823712015Interaction of chromatin with a histone H1 containing swapped N- and C-terminal domains.3
254821322015PcG methylation of the HIST1 cluster defines an epigenetic marker of acute myeloid leukemia.5
261823712015Interaction of chromatin with a histone H1 containing swapped N- and C-terminal domains.3
245257342014The C-terminal domain (CTD) in linker histones antagonizes anti-apoptotic proteins to modulate apoptotic outcomes at the mitochondrion.4
246016432014Histone H1 phosphorylation in breast cancer.21
245257342014The C-terminal domain (CTD) in linker histones antagonizes anti-apoptotic proteins to modulate apoptotic outcomes at the mitochondrion.4
246016432014Histone H1 phosphorylation in breast cancer.21
214258002011The multifunctional protein nucleophosmin (NPM1) is a human linker histone H1 chaperone.35
219407932011Role of Template Activating Factor-I as a chaperone in linker histone dynamics.24
214258002011The multifunctional protein nucleophosmin (NPM1) is a human linker histone H1 chaperone.35

Citation

Dessen P

H1-1 (H1.1 linker histone, cluster member)

Atlas Genet Cytogenet Oncol Haematol. 2004-05-01

Online version: http://atlasgeneticsoncology.org/gene/124/h1-1-(h1-1-linker-histone-cluster-member)