Identity
HGNC
LOCATION
8q13.3
LOCUSID
ALIAS
GRIP1,KAT13C,NCoA-2,SRC2,TIF2,bHLHe75
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10499
MIM: 601993
HGNC: 7669
Ensembl: ENSG00000140396
Variants:
dbSNP: 10499
ClinVar: 10499
TCGA: ENSG00000140396
COSMIC: NCOA2
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447199 | Bipolar Disorder | Disease | Literature, MultilinkAnnotation | associated | 24718920 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37870842 | 2024 | Myxoid epithelioid smooth muscle tumor of the vulva: A distinct entity with MEF2D::NCOA2 gene fusion. | 0 |
| 37870842 | 2024 | Myxoid epithelioid smooth muscle tumor of the vulva: A distinct entity with MEF2D::NCOA2 gene fusion. | 0 |
| 36656711 | 2023 | VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis. | 4 |
| 36656711 | 2023 | VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis. | 4 |
| 34624096 | 2022 | ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells. | 7 |
| 36309571 | 2022 | A GRIP-1-EZH2 switch binding to GATA-4 is linked to the genesis of rhabdomyosarcoma through miR-29a. | 2 |
| 34624096 | 2022 | ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells. | 7 |
| 36309571 | 2022 | A GRIP-1-EZH2 switch binding to GATA-4 is linked to the genesis of rhabdomyosarcoma through miR-29a. | 2 |
| 33574497 | 2021 | Recurrent MEIS1-NCOA2/1 fusions in a subset of low-grade spindle cell sarcomas frequently involving the genitourinary and gynecologic tracts. | 8 |
| 33593309 | 2021 | PFKFB4 promotes lung adenocarcinoma progression via phosphorylating and activating transcriptional coactivator SRC-2. | 10 |
| 33647291 | 2021 | Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR). | 7 |
| 34067464 | 2021 | Establishment and Characterization of a Cell Line (S-RMS1) Derived from an Infantile Spindle Cell Rhabdomyosarcoma with SRF-NCOA2 Fusion Transcript. | 2 |
| 33574497 | 2021 | Recurrent MEIS1-NCOA2/1 fusions in a subset of low-grade spindle cell sarcomas frequently involving the genitourinary and gynecologic tracts. | 8 |
| 33593309 | 2021 | PFKFB4 promotes lung adenocarcinoma progression via phosphorylating and activating transcriptional coactivator SRC-2. | 10 |
| 33647291 | 2021 | Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR). | 7 |
Citation
Dessen P
NCOA2 (nuclear receptor coactivator 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/141
