Identity
HGNC
LOCATION
11p15.5
LOCUSID
ALIAS
C11orf43,GRDF,IGF-II,PP9974,SRS3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3481
MIM: 147470
HGNC: 5466
Ensembl: ENSG00000167244
Variants:
dbSNP: 3481
ClinVar: 3481
TCGA: ENSG00000167244
COSMIC: IGF2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713176 | Platinum compounds | Chemical | VariantAnnotation | associated | PD | 30672383 | |
| PA445204 | Ovarian Neoplasms | Disease | VariantAnnotation | associated | PD | 30672383 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38412676 | 2024 | Hsa_circ_0036872 has an important promotional effect in enhancing osteogenesis of dental pulp stem cells by regulating the miR-143-3p/IGF2 axis. | 1 |
| 38521788 | 2024 | Activation of the insulin receptor by insulin-like growth factor 2. | 0 |
| 38612776 | 2024 | IGF-1 and IGF-2 as Molecules Linked to Causes and Consequences of Obesity from Fetal Life to Adulthood: A Systematic Review. | 0 |
| 38687996 | 2024 | Association of IGF-1 and IGF-2 genotypes with respiratory muscle strength in individuals with COPD: A cross-sectional study. | 0 |
| 38701040 | 2024 | The associations of IGF2, IGF2R and IGF2BP2 gene polymorphisms with gestational diabetes mellitus: A case-control study. | 0 |
| 38874740 | 2024 | Unmasking early colorectal cancer clues: in silico and in vitro investigation of downregulated IGF2, SOCS1, MLH1, and CACNA1G in SSA polyps. | 0 |
| 38412676 | 2024 | Hsa_circ_0036872 has an important promotional effect in enhancing osteogenesis of dental pulp stem cells by regulating the miR-143-3p/IGF2 axis. | 1 |
| 38521788 | 2024 | Activation of the insulin receptor by insulin-like growth factor 2. | 0 |
| 38612776 | 2024 | IGF-1 and IGF-2 as Molecules Linked to Causes and Consequences of Obesity from Fetal Life to Adulthood: A Systematic Review. | 0 |
| 38687996 | 2024 | Association of IGF-1 and IGF-2 genotypes with respiratory muscle strength in individuals with COPD: A cross-sectional study. | 0 |
| 38701040 | 2024 | The associations of IGF2, IGF2R and IGF2BP2 gene polymorphisms with gestational diabetes mellitus: A case-control study. | 0 |
| 38874740 | 2024 | Unmasking early colorectal cancer clues: in silico and in vitro investigation of downregulated IGF2, SOCS1, MLH1, and CACNA1G in SSA polyps. | 0 |
| 36739453 | 2023 | Noncanonical regulation of imprinted gene Igf2 by amyloid-beta 1-42 in Alzheimer's disease. | 4 |
| 36780225 | 2023 | Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma. | 2 |
| 36901760 | 2023 | Synergic Action of Insulin-like Growth Factor-2 and miRNA-483 in Pterygium Pathogenesis. | 3 |
Citation
Dessen P
IGF2 (insulin like growth factor 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/159
