Identity
HGNC
LOCATION
15q15.3
LOCUSID
ALIAS
53BP1,TDRD30,p202,p53BP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7158
MIM: 605230
HGNC: 11999
Ensembl: ENSG00000067369
Variants:
dbSNP: 7158
ClinVar: 7158
TCGA: ENSG00000067369
COSMIC: TP53BP1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38173016 | 2024 | Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging. | 0 |
| 38227944 | 2024 | The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage. | 0 |
| 38244928 | 2024 | Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer. | 4 |
| 38547292 | 2024 | Control of cell proliferation by memories of mitosis. | 2 |
| 38554279 | 2024 | BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks. | 0 |
| 38821984 | 2024 | Evolved histone tail regulates 53BP1 recruitment at damaged chromatin. | 0 |
| 38173016 | 2024 | Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging. | 0 |
| 38227944 | 2024 | The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage. | 0 |
| 38244928 | 2024 | Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer. | 4 |
| 38547292 | 2024 | Control of cell proliferation by memories of mitosis. | 2 |
| 38554279 | 2024 | BRCA1 and 53BP1 regulate reprogramming efficiency by mediating DNA repair pathway choice at replication-associated double-strand breaks. | 0 |
| 38821984 | 2024 | Evolved histone tail regulates 53BP1 recruitment at damaged chromatin. | 0 |
| 36606487 | 2023 | Incorporation of 53BP1 into phase-separated bodies in cancer cells during aberrant mitosis. | 0 |
| 36642815 | 2023 | DNA damage-induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation. | 5 |
| 36794849 | 2023 | HDGFRP3 interaction with 53BP1 promotes DNA double-strand break repair. | 5 |
Citation
Dessen P
TP53BP1 (tumor protein p53 binding protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/189/tp53bp1-(tumor-protein-p53-binding-protein-1)
