Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1950
MIM: 131530
HGNC: 3229
Ensembl: ENSG00000138798
Variants:
dbSNP: 1950
ClinVar: 1950
TCGA: ENSG00000138798
COSMIC: EGF
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000138798 | ENST00000265171 | P01133 |
| ENSG00000138798 | ENST00000503392 | P01133 |
| ENSG00000138798 | ENST00000509793 | P01133 |
| ENSG00000138798 | ENST00000652245 | A0A494C018 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10040 | cetuximab | Chemical | ClinicalAnnotation, Pathway | associated | PD | 16788380, 18349392, 23959273, 27897268 | |
| PA162373091 | panitumumab | Chemical | Pathway | associated | |||
| PA445503 | Rectal Neoplasms | Disease | ClinicalAnnotation | associated | PD | 16788380, 18349392, 23959273, 27897268 | |
| PA446108 | Colorectal Neoplasms | Disease | ClinicalAnnotation | associated | PD | 16788380, 18349392, 23959273, 27897268 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38338748 | 2024 | Searching for EGF Fragments Recreating the Outer Sphere of the Growth Factor Involved in Receptor Interactions. | 0 |
| 38518721 | 2024 | NRF2 regulates EGF stability through OTUD4 in lung adenocarcinoma. | 0 |
| 38338748 | 2024 | Searching for EGF Fragments Recreating the Outer Sphere of the Growth Factor Involved in Receptor Interactions. | 0 |
| 38518721 | 2024 | NRF2 regulates EGF stability through OTUD4 in lung adenocarcinoma. | 0 |
| 36342644 | 2023 | Urinary epidermal growth factor/monocyte chemotactic peptide 1 ratio as non-invasive predictor of Mayo clinic imaging classes in autosomal dominant polycystic kidney disease. | 0 |
| 36344779 | 2023 | Differences in salivary secretion and epidermal growth factor concentrations in mild reflux esophagitis and non-erosive reflux disease. | 2 |
| 36437134 | 2023 | Common and rare variants of EGF increase the genetic risk of Alzheimer's disease as revealed by targeted sequencing of growth factors in Han Chinese. | 1 |
| 37138025 | 2023 | Potential therapeutic target of EGF on bile duct ligation model and biliary atresia children. | 0 |
| 37658772 | 2023 | The association of epidermal growth factor variant with oral squamous cell carcinoma. | 0 |
| 37686213 | 2023 | EGF, TGF-α and Amphiregulin Differently Regulate Endometrium-Derived Mesenchymal Stromal/Stem Cells. | 1 |
| 37853459 | 2023 | RIZ2 at the crossroad of the EGF/EGFR signaling in colorectal cancer. | 1 |
| 37894950 | 2023 | EGF-Enhanced GnRH-II Regulation in Decidual Stromal Cell Motility through Twist and N-Cadherin Signaling. | 0 |
| 36342644 | 2023 | Urinary epidermal growth factor/monocyte chemotactic peptide 1 ratio as non-invasive predictor of Mayo clinic imaging classes in autosomal dominant polycystic kidney disease. | 0 |
| 36344779 | 2023 | Differences in salivary secretion and epidermal growth factor concentrations in mild reflux esophagitis and non-erosive reflux disease. | 2 |
| 36437134 | 2023 | Common and rare variants of EGF increase the genetic risk of Alzheimer's disease as revealed by targeted sequencing of growth factors in Han Chinese. | 1 |
Citation
Dessen P
EGF (epidermal growth factor)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/198/egf
