Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7012
MIM: 602322
HGNC: 11727
Ensembl: ENSG00000277925
Variants:
dbSNP: 7012
ClinVar: 7012
TCGA: ENSG00000277925
COSMIC: TERC
RNA/Proteins
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443450 | Asthma | Disease | MultilinkAnnotation | associated | 26720789 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38606545 | 2024 | Expanding the understanding of telomere biology disorder with reports from two families harboring variants in ZCCHC8 and TERC. | 1 |
| 38641551 | 2024 | Clinical mutations in the TERT and TERC genes coding for telomerase components induced oxidative stress, DNA damage at telomeres and cell apoptosis besides decreased telomerase activity. | 0 |
| 38606545 | 2024 | Expanding the understanding of telomere biology disorder with reports from two families harboring variants in ZCCHC8 and TERC. | 1 |
| 38641551 | 2024 | Clinical mutations in the TERT and TERC genes coding for telomerase components induced oxidative stress, DNA damage at telomeres and cell apoptosis besides decreased telomerase activity. | 0 |
| 37424004 | 2023 | TERC haploid cell reprogramming: a novel therapeutic strategy for aplastic anemia. | 1 |
| 37424004 | 2023 | TERC haploid cell reprogramming: a novel therapeutic strategy for aplastic anemia. | 1 |
| 35323972 | 2022 | Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity. | 8 |
| 36006930 | 2022 | Mutations in the TERC template sequence can be incorporated into the telomeres of human tumors. | 1 |
| 35323972 | 2022 | Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity. | 8 |
| 36006930 | 2022 | Mutations in the TERC template sequence can be incorporated into the telomeres of human tumors. | 1 |
| 32937184 | 2021 | The influence of TERC, TERT and ACYP2 genes polymorphisms on plasma telomerase concentration, telomeres length and T2DM. | 4 |
| 33407441 | 2021 | TERT rs2736100 and TERC rs16847897 genotypes moderate the association between internalizing mental disorders and accelerated telomere length attrition among HIV+ children and adolescents in Uganda. | 3 |
| 33450357 | 2021 | Long non-coding RNAs at work on telomeres: Functions and implications in cancer therapy. | 15 |
| 33763035 | 2021 | Prognostic Association of TERC, TERT Gene Polymorphism, and Leukocyte Telomere Length in Acute Heart Failure: A Prospective Study. | 6 |
| 34353901 | 2021 | Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis. | 7 |
Citation
Dessen P
TERC (telomerase RNA component)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/255/terc-(telomerase-rna-component)
