TERC (telomerase RNA component)

2003-02-01  

Identity

HGNC
TERC
LOCATION
3q26.2
LOCUSID
7012
ALIAS
DKCA1,PFBMFT2,SCARNA19,TR,TRC3,hTR

Other Information

Locus ID:

NCBI: 7012
MIM: 602322
HGNC: 11727
Ensembl: ENSG00000277925

Variants:

dbSNP: 7012
ClinVar: 7012
TCGA: ENSG00000277925
COSMIC: TERC

RNA/Proteins

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA443450AsthmaDiseaseMultilinkAnnotationassociated26720789

References

Pubmed IDYearTitleCitations
386065452024Expanding the understanding of telomere biology disorder with reports from two families harboring variants in ZCCHC8 and TERC.1
386415512024Clinical mutations in the TERT and TERC genes coding for telomerase components induced oxidative stress, DNA damage at telomeres and cell apoptosis besides decreased telomerase activity.0
386065452024Expanding the understanding of telomere biology disorder with reports from two families harboring variants in ZCCHC8 and TERC.1
386415512024Clinical mutations in the TERT and TERC genes coding for telomerase components induced oxidative stress, DNA damage at telomeres and cell apoptosis besides decreased telomerase activity.0
374240042023TERC haploid cell reprogramming: a novel therapeutic strategy for aplastic anemia.1
374240042023TERC haploid cell reprogramming: a novel therapeutic strategy for aplastic anemia.1
353239722022Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity.8
360069302022Mutations in the TERC template sequence can be incorporated into the telomeres of human tumors.1
353239722022Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity.8
360069302022Mutations in the TERC template sequence can be incorporated into the telomeres of human tumors.1
329371842021The influence of TERC, TERT and ACYP2 genes polymorphisms on plasma telomerase concentration, telomeres length and T2DM.4
334074412021TERT rs2736100 and TERC rs16847897 genotypes moderate the association between internalizing mental disorders and accelerated telomere length attrition among HIV+ children and adolescents in Uganda.3
334503572021Long non-coding RNAs at work on telomeres: Functions and implications in cancer therapy.15
337630352021Prognostic Association of TERC, TERT Gene Polymorphism, and Leukocyte Telomere Length in Acute Heart Failure: A Prospective Study.6
343539012021Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis.7

Citation

Dessen P

TERC (telomerase RNA component)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/255/terc-(telomerase-rna-component)