CDH6 (cadherin 6)

2003-06-01  

Identity

HGNC
LOCATION
5p13.3
LOCUSID
ALIAS
CAD6,KCAD
FUSION GENES

Other Information

Locus ID:

NCBI: 1004
MIM: 603007
HGNC: 1765
Ensembl: ENSG00000113361

Variants:

dbSNP: 1004
ClinVar: 1004
TCGA: ENSG00000113361
COSMIC: CDH6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000113361ENST00000265071P55285
ENSG00000113361ENST00000514738D6RF86

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Cell-Cell communicationREACTOMER-HSA-1500931
Cell junction organizationREACTOMER-HSA-446728
Cell-cell junction organizationREACTOMER-HSA-421270
Adherens junctions interactionsREACTOMER-HSA-418990

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
206348872010Polycomb target genes are silenced in multiple myeloma.45
240694222013Cadherin 6 is a new RUNX2 target in TGF-β signalling pathway.26
275935572016Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinoma.10
296283052018miR-223-3p Inhibits Human Osteosarcoma Metastasis and Progression by Directly Targeting CDH6.10
262851592016Concomitant high expression of BRAFV600E, P-cadherin and cadherin 6 is associated with High TNM stage and lymph node metastasis in conventional papillary thyroid carcinoma.2
308065282019Low endometrial beta-catenin and cadherins expression patterns are predictive for primary infertility and recurrent pregnancy loss.1

Citation

Dessen P

CDH6 (cadherin 6)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40028/cdh6-(cadherin-6)