Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1020
MIM: 123831
HGNC: 1774
Ensembl: ENSG00000164885
Variants:
dbSNP: 1020
ClinVar: 1020
TCGA: ENSG00000164885
COSMIC: CDK5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000164885 | ENST00000297518 | Q00535 |
| ENSG00000164885 | ENST00000297518 | A0A0S2Z355 |
| ENSG00000164885 | ENST00000485972 | Q00535 |
| ENSG00000164885 | ENST00000485972 | A0A090N7W4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA33639 | PPP1R1B | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38742811 | 2024 | miR-4645-3p attenuates podocyte injury and mitochondrial dysfunction in diabetic kidney disease by targeting Cdk5. | 0 |
| 38742811 | 2024 | miR-4645-3p attenuates podocyte injury and mitochondrial dysfunction in diabetic kidney disease by targeting Cdk5. | 0 |
| 36853485 | 2023 | Comprehensive analysis of CDK5 as a novel biomarker for progression in esophageal cancer. | 1 |
| 36995937 | 2023 | CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth. | 9 |
| 37039746 | 2023 | Higher Levels of Tumour-Infiltrating Lymphocytes (TILs) are Associated with a Better Prognosis, While CDK5 Plays a Different Role Between Nonmetastatic and Metastatic Colonic Carcinoma. | 2 |
| 37976261 | 2023 | Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy. | 0 |
| 37982142 | 2023 | Activation of cyclin-dependent kinase 5 broadens action potentials in human sensory neurons. | 1 |
| 36853485 | 2023 | Comprehensive analysis of CDK5 as a novel biomarker for progression in esophageal cancer. | 1 |
| 36995937 | 2023 | CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth. | 9 |
| 37039746 | 2023 | Higher Levels of Tumour-Infiltrating Lymphocytes (TILs) are Associated with a Better Prognosis, While CDK5 Plays a Different Role Between Nonmetastatic and Metastatic Colonic Carcinoma. | 2 |
| 37976261 | 2023 | Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy. | 0 |
| 37982142 | 2023 | Activation of cyclin-dependent kinase 5 broadens action potentials in human sensory neurons. | 1 |
| 34773219 | 2022 | Phosphorylation of CRMP2 by Cdk5 Negatively Regulates the Surface Delivery and Synaptic Function of AMPA Receptors. | 2 |
| 34875451 | 2022 | MiR-142-5p directly targets cyclin-dependent kinase 5-mediated upregulation of the inflammatory process in acquired middle ear cholesteatoma. | 4 |
| 35143052 | 2022 | Cyclin-dependent kinase 5 promotes the growth of tongue squamous cell carcinoma through the microRNA 513c-5p/cell division cycle 25B pathway and is associated with a poor prognosis. | 3 |
Citation
Dessen P
CDK5 (cyclin dependent kinase 5)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40033/cdk5-(cyclin-dependent-kinase-5)
