Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10752
MIM: 607416
HGNC: 1939
Ensembl: ENSG00000134121
Variants:
dbSNP: 10752
ClinVar: 10752
TCGA: ENSG00000134121
COSMIC: CHL1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Axon guidance | REACTOME | R-HSA-422475 |
| L1CAM interactions | REACTOME | R-HSA-373760 |
| CHL1 interactions | REACTOME | R-HSA-447041 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33054469 | 2022 | Analysis of the functional sequences in the promoter region of the human adhesion molecule close homolog of L1. | 0 |
| 35262525 | 2022 | Expression of CHL1 in Clear Cell Renal Cell Carcinoma and its Association With Prognosis. | 3 |
| 33054469 | 2022 | Analysis of the functional sequences in the promoter region of the human adhesion molecule close homolog of L1. | 0 |
| 35262525 | 2022 | Expression of CHL1 in Clear Cell Renal Cell Carcinoma and its Association With Prognosis. | 3 |
| 31614370 | 2021 | Reduced Expression of Chl1 gene Impairs Insulin Secretion by Down-Regulating the Expression of Key Molecules of β-cell Function. | 11 |
| 33453020 | 2021 | Cell adhesion molecule L1 like plays a role in the pathogenesis of idiopathic hypogonadotropic hypogonadism. | 3 |
| 34718336 | 2021 | Exosomal miR-338-3p suppresses non-small-cell lung cancer cells metastasis by inhibiting CHL1 through the MAPK signaling pathway. | 13 |
| 31614370 | 2021 | Reduced Expression of Chl1 gene Impairs Insulin Secretion by Down-Regulating the Expression of Key Molecules of β-cell Function. | 11 |
| 33453020 | 2021 | Cell adhesion molecule L1 like plays a role in the pathogenesis of idiopathic hypogonadotropic hypogonadism. | 3 |
| 34718336 | 2021 | Exosomal miR-338-3p suppresses non-small-cell lung cancer cells metastasis by inhibiting CHL1 through the MAPK signaling pathway. | 13 |
| 32557322 | 2020 | Downregulation of Adhesion Molecule CHL1 in B Cells but Not T Cells of Patients with Major Depression and in the Brain of Mice with Chronic Stress. | 10 |
| 33326488 | 2020 | Ezrin interacts with the tumor suppressor CHL1 and promotes neuronal differentiation of human neuroblastoma. | 3 |
| 32557322 | 2020 | Downregulation of Adhesion Molecule CHL1 in B Cells but Not T Cells of Patients with Major Depression and in the Brain of Mice with Chronic Stress. | 10 |
| 33326488 | 2020 | Ezrin interacts with the tumor suppressor CHL1 and promotes neuronal differentiation of human neuroblastoma. | 3 |
| 30622339 | 2019 | Loss of cell adhesion molecule L1 like promotes tumor growth and metastasis in esophageal squamous cell carcinoma. | 15 |
Citation
Dessen P
CHL1 (cell adhesion molecule L1 like)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40076/chl1-(cell-adhesion-molecule-l1-like)
