CHRDL2 (chordin like 2)

2003-10-01 Affiliation

Identity

HGNC

CHRDL2

LOCATION

11q13.4

LOCUSID

25884

ALIAS

BNF1,CHL2

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 25884
MIM: 613127
HGNC: 24168
Ensembl: ENSG00000054938

Variants:

dbSNP: 25884
ClinVar: 25884
TCGA: ENSG00000054938
COSMIC: CHRDL2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000054938	ENST00000263671	Q6WN34
ENSG00000054938	ENST00000376324	A8MQ10
ENSG00000054938	ENST00000376332	Q6WN34
ENSG00000054938	ENST00000525413	H0YDT1
ENSG00000054938	ENST00000528471	Q6WN34
ENSG00000054938	ENST00000528789	Q6WN33
ENSG00000054938	ENST00000529912	H0YCU0
ENSG00000054938	ENST00000534276	Q6WN34
ENSG00000054938	ENST00000622063	A0A087WZH6

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
36206931	2022	CHRDL2 promotes cell proliferation by activating the YAP/TAZ signaling pathway in gastric cancer.	3
36206931	2022	CHRDL2 promotes cell proliferation by activating the YAP/TAZ signaling pathway in gastric cancer.	3
33245175	2021	CHRDL2 promotes osteosarcoma cell proliferation and metastasis through the BMP-9/PI3K/AKT pathway.	15
33245175	2021	CHRDL2 promotes osteosarcoma cell proliferation and metastasis through the BMP-9/PI3K/AKT pathway.	15
28009989	2017	Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis.	7
28009989	2017	Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis.	7
19453261	2009	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	23
19453261	2009	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	23
14660436	2004	A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage.	39
15094188	2004	hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation.	9
14660436	2004	A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage.	39
15094188	2004	hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation.	9

Citation

Dessen P

CHRDL2 (chordin like 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-10-01

Online version: http://atlasgeneticsoncology.org/gene/40080/css/lib/haematological-explorer/hgnc