Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1196
MIM: 602989
HGNC: 2069
Ensembl: ENSG00000176444
Variants:
dbSNP: 1196
ClinVar: 1196
TCGA: ENSG00000176444
COSMIC: CLK2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000176444 | ENST00000355560 | B1AVT0 |
| ENSG00000176444 | ENST00000361168 | P49760 |
| ENSG00000176444 | ENST00000368361 | P49760 |
| ENSG00000176444 | ENST00000368361 | A8K7I0 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35293765 | 2022 | CDC Like Kinase 2 plays an oncogenic role in colorectal cancer via modulating the Wnt/β-catenin signaling. | 3 |
| 35293765 | 2022 | CDC Like Kinase 2 plays an oncogenic role in colorectal cancer via modulating the Wnt/β-catenin signaling. | 3 |
| 33721432 | 2021 | CLK2 promotes occurrence and development of non-small cell lung cancer. | 4 |
| 33721432 | 2021 | CLK2 promotes occurrence and development of non-small cell lung cancer. | 4 |
| 27050366 | 2016 | Cdc2-like kinase 2 is a key regulator of the cell cycle via FOXO3a/p27 in glioblastoma. | 27 |
| 27126587 | 2016 | Clks 1, 2 and 4 prevent chromatin breakage by regulating the Aurora B-dependent abscission checkpoint. | 36 |
| 27050366 | 2016 | Cdc2-like kinase 2 is a key regulator of the cell cycle via FOXO3a/p27 in glioblastoma. | 27 |
| 27126587 | 2016 | Clks 1, 2 and 4 prevent chromatin breakage by regulating the Aurora B-dependent abscission checkpoint. | 36 |
| 25670169 | 2015 | CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer. | 55 |
| 25670169 | 2015 | CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer. | 55 |
| 23376537 | 2013 | The highly conserved LAMMER/CLK2 protein kinases prevent germ cell overproliferation in Drosophila. | 17 |
| 23376537 | 2013 | The highly conserved LAMMER/CLK2 protein kinases prevent germ cell overproliferation in Drosophila. | 17 |
| 21682887 | 2011 | Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy. | 41 |
| 21682887 | 2011 | Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy. | 41 |
| 20682768 | 2010 | Phosphorylation of CLK2 at serine 34 and threonine 127 by AKT controls cell survival after ionizing radiation. | 16 |
Citation
Dessen P
CLK2 (CDC like kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40103/clk2-(cdc-like-kinase-2)
