CPNE3 (copine 3)

2003-05-01  

Identity

HGNC
LOCATION
8q21.3
LOCUSID
ALIAS
CPN3,PRO1071
FUSION GENES

Other Information

Locus ID:

NCBI: 8895
MIM: 604207
HGNC: 2316
Ensembl: ENSG00000085719

Variants:

dbSNP: 8895
ClinVar: 8895
TCGA: ENSG00000085719
COSMIC: CPNE3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000085719ENST00000517391H0YB26
ENSG00000085719ENST00000517490O75131
ENSG00000085719ENST00000517490A0A024R994
ENSG00000085719ENST00000522240E5RFT7
ENSG00000085719ENST00000523469E5RHZ0
ENSG00000085719ENST00000620393A0A087WUS8
ENSG00000085719ENST00000621245A0A087WXR6
ENSG00000085719ENST00000621526A0A0G2JMP5
ENSG00000085719ENST00000621783A0A087WYQ3

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382939842024[High expression of CPNE3 correlates with poor long-term prognosis of gastric cancer by inhibiting cell apoptosis via activating PI3K/AKT signaling].0
384934262024YAP1-CPNE3 positive feedback pathway promotes gastric cancer cell progression.0
382939842024[High expression of CPNE3 correlates with poor long-term prognosis of gastric cancer by inhibiting cell apoptosis via activating PI3K/AKT signaling].0
384934262024YAP1-CPNE3 positive feedback pathway promotes gastric cancer cell progression.0
337252132021Upregulation of CPNE3 suppresses invasion, migration and proliferation of glioblastoma cells through FAK pathway inactivation.6
337672972021CPNE3 moderates the association between anxiety and working memory.3
337252132021Upregulation of CPNE3 suppresses invasion, migration and proliferation of glioblastoma cells through FAK pathway inactivation.6
337672972021CPNE3 moderates the association between anxiety and working memory.3
292971772019Low CPNE3 expression is associated with risk of acute myocardial infarction: A feasible genetic marker of acute myocardial infarction in patients with stable coronary artery disease.15
300781892019Circulating exosomal CPNE3 as a diagnostic and prognostic biomarker for colorectal cancer.64
292971772019Low CPNE3 expression is associated with risk of acute myocardial infarction: A feasible genetic marker of acute myocardial infarction in patients with stable coronary artery disease.15
300781892019Circulating exosomal CPNE3 as a diagnostic and prognostic biomarker for colorectal cancer.64
298672022018Epithelial membrane protein 1 promotes tumor metastasis by enhancing cell migration via copine-III and Rac1.36
298672022018Epithelial membrane protein 1 promotes tumor metastasis by enhancing cell migration via copine-III and Rac1.36
286708592017High expression of CPNE3 predicts adverse prognosis in acute myeloid leukemia.10

Citation

Dessen P

CPNE3 (copine 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40139/cpne3-(copine-3)