CREG1 (cellular repressor of E1A stimulated genes 1)

2003-05-01  

Identity

HGNC
LOCATION
1q24.2
LOCUSID
ALIAS
CREG

Other Information

Locus ID:

NCBI: 8804
MIM: 618055
HGNC: 2351
Ensembl: ENSG00000143162

Variants:

dbSNP: 8804
ClinVar: 8804
TCGA: ENSG00000143162
COSMIC: CREG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143162ENST00000370509O75629
ENSG00000143162ENST00000466652A0A3B3IRL2

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

References

Pubmed IDYearTitleCitations
195361752009Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study.30
190646102009Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.16
235183892013MicroRNA-31 controls phenotypic modulation of human vascular smooth muscle cells by regulating its target gene cellular repressor of E1A-stimulated genes.16
212632172011CREG1 enhances p16(INK4a) -induced cellular senescence.13
200600032010Cellular repressor of E1A-stimulated genes inhibits human vascular smooth muscle cell apoptosis via blocking P38/JNK MAP kinase activation.12
163444692005The crystal structure of CREG, a secreted glycoprotein involved in cellular growth and differentiation.11
182679542008CREG promotes a mature smooth muscle cell phenotype and reduces neointimal formation in balloon-injured rat carotid artery.10
194138952009Cellular repressor of E1A-stimulated genes attenuates cardiac hypertrophy and fibrosis.10
218722522011Overexpression of CREG attenuates atherosclerotic endothelium apoptosis via VEGF/PI3K/AKT pathway.10
197699652009CREG inhibits migration of human vascular smooth muscle cells by mediating IGF-II endocytosis.9

Citation

Dessen P

CREG1 (cellular repressor of E1A stimulated genes 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40146/creg1-(cellular-repressor-of-e1a-stimulated-genes-1)