CSF3 (colony stimulating factor 3)

2003-02-01  

Identity

HGNC
CSF3
LOCATION
17q21.1
LOCUSID
1440
ALIAS
C17orf33,CSF3OS,GCSF

Other Information

Locus ID:

NCBI: 1440
MIM: 138970
HGNC: 2438
Ensembl: ENSG00000108342

Variants:

dbSNP: 1440
ClinVar: 1440
TCGA: ENSG00000108342
COSMIC: CSF3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108342ENST00000225474P09919
ENSG00000108342ENST00000331769Q8N4W3
ENSG00000108342ENST00000394148P09919
ENSG00000108342ENST00000394149P09919
ENSG00000108342ENST00000394149Q6FH65
ENSG00000108342ENST00000577675J3KTH8
ENSG00000108342ENST00000579852J3QRD4
ENSG00000108342ENST00000583218J3QRX2

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Jak-STAT signaling pathwayKEGGko04630
Hematopoietic cell lineageKEGGko04640
Cytokine-cytokine receptor interactionKEGGhsa04060
Jak-STAT signaling pathwayKEGGhsa04630
Hematopoietic cell lineageKEGGhsa04640
MalariaKEGGko05144
MalariaKEGGhsa05144
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147
Interleukin-10 signalingREACTOMER-HSA-6783783
IL-17 signaling pathwayKEGGko04657
IL-17 signaling pathwayKEGGhsa04657

References

Pubmed IDYearTitleCitations
378248222024G-CSF reshapes the cytosolic PCNA scaffold and modulates glycolysis in neutrophils.1
378248222024G-CSF reshapes the cytosolic PCNA scaffold and modulates glycolysis in neutrophils.1
369110972023Tumor-derived GCSF Alters Tumor and Systemic Immune System Cell Subset Composition and Signaling.0
371697372023p140Cap inhibits β-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response.3
379222892023Serum cytokines MCP-1 and GCS-F as potential biomarkers in pediatric inflammatory bowel disease.0
369110972023Tumor-derived GCSF Alters Tumor and Systemic Immune System Cell Subset Composition and Signaling.0
371697372023p140Cap inhibits β-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response.3
379222892023Serum cytokines MCP-1 and GCS-F as potential biomarkers in pediatric inflammatory bowel disease.0
357816032022G-CSF promotes the viability and angiogenesis of injured liver via direct effects on the liver cells.2
361754652022Elevated G-CSF, IL8, and HGF in patients with definite Meniere's disease may indicate the role of NET formation in triggering autoimmunity and autoinflammation.3
357816032022G-CSF promotes the viability and angiogenesis of injured liver via direct effects on the liver cells.2
361754652022Elevated G-CSF, IL8, and HGF in patients with definite Meniere's disease may indicate the role of NET formation in triggering autoimmunity and autoinflammation.3
331886432021Investigating apoptotic, inflammatory, and growth markers in poor responders undergoing natural in vitro fertilization cycles: a pilot study.1
333932052021M2 macrophage-derived G-CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy.38
336067882021Colony-stimulating factor 3 signaling in colon and rectal cancers: Immune response and CMS classification in TCGA data.9

Citation

Dessen P

CSF3 (colony stimulating factor 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40164/csf3-(colony-stimulating-factor-3)