CSNK1D (casein kinase 1 delta)

2003-11-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
ASPS,CKI-delta,CKId,CKIdelta,FASPS2,HCKID
FUSION GENES

Other Information

Locus ID:

NCBI: 1453
MIM: 600864
HGNC: 2452
Ensembl: ENSG00000141551

Variants:

dbSNP: 1453
ClinVar: 1453
TCGA: ENSG00000141551
COSMIC: CSNK1D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000141551ENST00000269361H0Y2N6
ENSG00000141551ENST00000314028P48730
ENSG00000141551ENST00000392334P48730
ENSG00000141551ENST00000398519H7BYT1
ENSG00000141551ENST00000403276B4DLF1
ENSG00000141551ENST00000580446J3QQI9
ENSG00000141551ENST00000580784J3QQU8
ENSG00000141551ENST00000581660J3QS70
ENSG00000141551ENST00000584672J3KRM8
ENSG00000141551ENST00000585026J3KRS6

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Hedgehog signaling pathwayKEGGko04340
Gap junctionKEGGko04540
Circadian rhythmKEGGko04710
Hedgehog signaling pathwayKEGGhsa04340
Gap junctionKEGGhsa04540
Circadian rhythmKEGGhsa04710
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
COPII (Coat Protein 2) Mediated Vesicle TransportREACTOMER-HSA-204005
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Anchoring of the basal body to the plasma membraneREACTOMER-HSA-5620912
Gene ExpressionREACTOMER-HSA-74160
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
Mitotic G2-G2/M phasesREACTOMER-HSA-453274
G2/M TransitionREACTOMER-HSA-69275
Regulation of PLK1 Activity at G2/M TransitionREACTOMER-HSA-2565942
Centrosome maturationREACTOMER-HSA-380287
Recruitment of mitotic centrosome proteins and complexesREACTOMER-HSA-380270
Loss of proteins required for interphase microtubule organization from the centrosomeREACTOMER-HSA-380284
Loss of Nlp from mitotic centrosomesREACTOMER-HSA-380259
Circadian ClockREACTOMER-HSA-400253
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
AURKA Activation by TPX2REACTOMER-HSA-8854518
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366416752023Casein Kinase 1δ Phosphorylates TDP-43 and Suppresses Its Function in Tau mRNA Processing.0
372085652023CSNK1D-mediated phosphorylation of HNRNPA2B1 induces miR-25-3p/miR-93-5p maturation to promote prostate cancer cell proliferation and migration through m(6)A-dependent manner.1
376887712023Prognostic value and immunological role of CSNK1D in human cancers.1
366416752023Casein Kinase 1δ Phosphorylates TDP-43 and Suppresses Its Function in Tau mRNA Processing.0
372085652023CSNK1D-mediated phosphorylation of HNRNPA2B1 induces miR-25-3p/miR-93-5p maturation to promote prostate cancer cell proliferation and migration through m(6)A-dependent manner.1
376887712023Prognostic value and immunological role of CSNK1D in human cancers.1
334203622021β-Trcp and CK1δ-mediated degradation of LZTS2 activates PI3K/AKT signaling to drive tumorigenesis and metastasis in hepatocellular carcinoma.12
342039782021CK1δ-Derived Peptides as Novel Tools Inhibiting the Interactions between CK1δ and APP695 to Modulate the Pathogenic Metabolism of APP.1
342800052021Upregulation of Stress-Induced Protein Kinase CK1 Delta is associated with a Poor Prognosis for patients with Hepatocellular Carcinoma.6
334203622021β-Trcp and CK1δ-mediated degradation of LZTS2 activates PI3K/AKT signaling to drive tumorigenesis and metastasis in hepatocellular carcinoma.12
342039782021CK1δ-Derived Peptides as Novel Tools Inhibiting the Interactions between CK1δ and APP695 to Modulate the Pathogenic Metabolism of APP.1
342800052021Upregulation of Stress-Induced Protein Kinase CK1 Delta is associated with a Poor Prognosis for patients with Hepatocellular Carcinoma.6
323219362020CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.5
324304842020Targeting Casein Kinase 1 Delta Sensitizes Pancreatic and Bladder Cancer Cells to Gemcitabine Treatment by Upregulating Deoxycytidine Kinase.5
323219362020CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.5

Citation

Dessen P

CSNK1D (casein kinase 1 delta)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/40169/csnk1d-(casein-kinase-1-delta)