CTDSP2 (CTD small phosphatase 2)

2003-02-01  

Identity

HGNC
CTDSP2
LOCATION
12q14.1
LOCUSID
10106
ALIAS
OS4,PSR2,SCP2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10106
MIM: 608711
HGNC: 17077
Ensembl: ENSG00000175215

Variants:

dbSNP: 10106
ClinVar: 10106
TCGA: ENSG00000175215
COSMIC: CTDSP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175215ENST00000398073O14595
ENSG00000175215ENST00000398073A0A024RBA6
ENSG00000175215ENST00000547701F8W184
ENSG00000175215ENST00000548823F8W1I1
ENSG00000175215ENST00000549039H0YI29
ENSG00000175215ENST00000550144H0YI12
ENSG00000175215ENST00000551594F8VYL0

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Unfolded Protein Response (UPR)REACTOMER-HSA-381119
IRE1alpha activates chaperonesREACTOMER-HSA-381070
XBP1(S) activates chaperone genesREACTOMER-HSA-381038

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
317749102019Tumor suppressor properties of the small C-terminal domain phosphatases in non-small cell lung cancer.8
317749102019Tumor suppressor properties of the small C-terminal domain phosphatases in non-small cell lung cancer.8
259903252015FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1).16
259903252015FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1).16
167241082006Small carboxyl-terminal domain phosphatase 2 attenuates androgen-dependent transcription.14
170854342006Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.80
167241082006Small carboxyl-terminal domain phosphatase 2 attenuates androgen-dependent transcription.14
170854342006Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.80

Citation

Dessen P

CTDSP2 (CTD small phosphatase 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40188/ctdsp2-(ctd-small-phosphatase-2)